Tumor Microenvironment and Cancer Immunology, Immunotherapy
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Immunology".
Deadline for manuscript submissions: closed (15 June 2023) | Viewed by 487
Special Issue Editors
Interests: breast cancer; tumor microenvironment; cancer-associated fibroblasts; immunotherapy; cancer therapy; surgery; Immune; chemotherapy
Special Issue Information
Dear Colleagues,
It is well established that the tumor microenvironment (TME) plays a pivotal role in tumor initiation, progression and therapeutic resistance through dynamic interaction with cancer cells. The TME includes immune cells, stromal cells, the extracellular matrix (ECM), growth factors, nutrients, blood and lymphatic vessels, which serve as a sustained niche for cancer cells to proliferate and metastasize. With the increasingly profound understanding of the interconnection between malignant cells and microenvironmental components, the TME is now under investigation for its prominent role in cancer therapeutics. It is indispensable to explore the underlying mechanisms involved in the interrelationship between TME and cancer cells and the basis of therapeutic targets and drug resistance related to TME.
Potential topics include, but are not limited to:
- Crucial signaling in cancer cells that affects TME;
- Molecular mechanisms regulating the crosstalk between TME and cancer cells;
- Potential therapeutic targets on TME components and cancer cells;
- New strategies of cancer immunotherapy;
- TME and drug resistance in cancer;
- The functions of TME components in cancer progression.
Dr. Shaoquan Zheng
Dr. Peng Qu
Guest Editors
Manuscript Submission Information
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Keywords
- tumor microenvironment
- cancer-associated fibroblasts
- immunotherapy
