Molecular and Cellular Mechanisms of Cancers: Urothelial Cancer

Dear Colleagues,

Urothelial cancer, a prevalent malignancy affecting the urinary tract, has emerged as a critical focus of scientific inquiry within the broader context of cancer research. Urothelial cancer encompasses a group of cancers originating from the urothelial cells lining various parts of the urinary tract, including the bladder, urethra, and renal pelvis. The objective of this Special Issue is to delve into the molecular and cellular mechanisms underlying the initiation and progression of urothelial cancer, aiming to enhance our understanding of this malignancy at a deeper level.

Articles within this Special Issue will cover the pathogenic mechanisms, molecular foundations, and cellular signaling pathways associated with urothelial cancer, as well as the impact of individual variations in patients on tumor development. This Special Issue will also highlight emerging therapeutic strategies and drugs, along with their applications in clinical practice. Researchers and clinical practitioners can discover the latest scientific insights into urothelial cancer from these articles, contributing to improvements in diagnosis, treatment, and prognosis assessment.

By conducting in-depth research into the molecular and cellular mechanisms of urothelial cancer, there is potential to identify new therapeutic targets and biomarkers, providing robust support for personalized treatment and precision medicine. This Special Issue aims to offer a comprehensive and profound perspective for researchers, clinicians, and medical professionals, propelling scientific research and clinical advancements in the field of urothelial cancer.

We are pleased to invite you to contribute original articles, reviews, and communications. We look forward to your contributions to this Special Issue.

Dr. Marcello Tucci
Guest Editor

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• urothelial cancer
• bladder cancer
• transitional cell carcinoma
• molecular mechanisms
• cellular mechanisms
• oncogenesis
• tumor microenvironment
• biomarkers
• molecular signaling
• genetic alterations
• epigenetics
• immunotherapy
• targeted therapy
• precision medicine
• cancer metabolism
• apoptosis
• tumor suppressor genes
• oncogenes