Ion Channels in Pain: Mechanisms and Therapeutics
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cells of the Nervous System".
Deadline for manuscript submissions: 30 August 2024 | Viewed by 111
Special Issue Editors
Interests: chronic pain; sensory neurons; ion channels; neuron excitability; pain mechanisms; pain therapeutics
Interests: chronic pain; sensory neurons; ion channels; pain mechanisms; pain therapeutics
Special Issue Information
Dear Colleagues,
Many voltage-gated and ligand-gated ion channels are enriched in the sensory pathways of the central and peripheral nervous systems and are crucial for sensory physiology and pain pathogenesis. Pronociceptive ion channels are a major class of drug targets for modulating pain sensation and controlling chronic pain. A greater understanding of ion channel modulation in sensory pathways is not only important for delineating pain mechanisms but is also crucial for facilitating the development of new strategies for the treatment of pain.
This Special Issue aims to provide up-to-date information on the research topics related to sensory ion channels, their gene expression and mechanisms of regulation under physiological and pathophysiological conditions, novel small molecule compounds and biologics targeting ion channels, and new strategies for the treatment of pain. The studies may include experimental research and systematic reviews in this field and are expected to include new insights and challenges in researching ion channels in pain, ion channel regulatory interactomes, ion channels and neuronal excitability, novel biomarkers, and ion channel targeting strategies that have the potential to be developed as pain treatment tools. Submitted manuscripts should not have been published previously nor be under consideration for publication elsewhere (except for conference proceeding papers).
Prof. Dr. Hongwei Yu
Dr. Michelino Puopolo
Dr. Seung Min Shin
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- chronic pain
- sensory neurons
- ion channels
- pain mechanisms
- pain therapeutics
