Assessment and Rehabilitation of Cognitive Frailty Related to Ageing and Neurodegenerative Conditions

A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neurodegenerative Diseases".

Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 1606

Special Issue Editor


E-Mail Website
Guest Editor
Centre of Healthy Ageing and Wellness (H-CARE), Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
Interests: ageing and dementia studies; healthy brain; healthy ageing; prevention; mental health; cognition; psychosocial intervention

Special Issue Information

Dear Colleagues,

Cognitive frailty is a relatively new term that requires an in depth understanding to not only establish the clinical syndrome and its assessment for the purpose of early detection but also apply scientific evidence to reverse the course of cognitive frailty. Cognitive frailty (CF) is a clinical manifestation presenting with evidence of combined mild cognitive impairment (MCI) and physical frailty (PF). There is a clear lack of follow-up and longitudinal studies to advance our understanding of the impact of interventions in delaying or preventing this condition, which may play a vital role in reducing the risk of dementia. Like any other neurogenerative disorder, the major risk factor for cognitive frailty is advanced age. Cognitive frailty has been identified as a significant predictor of dementia, and recently emerging evidence indicates that early detection combined with concurrent cognitive and physical intervention has the potential to reverse the condition, thus preventing or delaying the onset of dementia. However, this approach requires an in depth understanding and thorough investigation of the assessment, detection, and rehabilitation (e.g., cognitive training, lifestyle intervention, multidomain intervention, etc.) of cognitive frailty in our efforts to improve brain health. 

In this Brain Sciences Special Issue, we invite researchers to submit work on a broad range of topics, from the basic to the advanced, in areas covering the early detection, screening, assessment, and rehabilitation of cognitive frailty related to ageing and neurodegenerative conditions. We look forward to assisting authors in sharing their findings in the form of original research articles and review articles.

Dr. Ponnusamy Subramaniam
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cognitive frailty
  • Alzheimer’s disease
  • dementia
  • cognitive impairment
  • physical frailty
  • prevention
  • risk reduction
  • screening
  • cognitive training
  • lifestyle intervention

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Review

8 pages, 2876 KiB  
Review
Biological Risk Factors Influencing Vascular Cognitive Impairments: A Review of the Evidence
by Silvina Iluț, Ştefan Cristian Vesa, Vitalie Văcăraș, Lavinia Brăiță, Vlad-Constantin Dăscălescu, Ioana Fantu and Dafin-Fior Mureșanu
Brain Sci. 2023, 13(7), 1094; https://doi.org/10.3390/brainsci13071094 - 19 Jul 2023
Cited by 1 | Viewed by 1079
Abstract
Vascular cognitive impairment encompasses several types of deficits, ranging from mild cognitive impairment to dementia. Cognitive reserve refers to the brain’s ability to balance damage and improve performance through certain types of brain networks. The purpose of this review was to assess the [...] Read more.
Vascular cognitive impairment encompasses several types of deficits, ranging from mild cognitive impairment to dementia. Cognitive reserve refers to the brain’s ability to balance damage and improve performance through certain types of brain networks. The purpose of this review was to assess the relationship between reserve in vascular impairment, specifically looking at whether cognitive impairment is influenced by cognitive reserve, identifying significant vascular risk factors and their pathological pathways. To achieve this purpose, a review covering these issues was conducted within the Embase, Cochrane, and PubMed database. A total of 657 scientific articles were found, and 33 papers were considered for the final analysis. We concluded that there is no consensus on the protective effects of brain reserve on cognitive impairment. Stroke and diabetes can be considered significant risk factors for vascular cognitive impairment, while hypertension is not as damaging as blood pressure variability, which structurally alters the brain through a variety of mechanisms. Full article
Show Figures

Figure 1

Back to TopTop