Epilepsy in Childhood and Adolescence: Where Do We Stand?
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Developmental Neuroscience".
Deadline for manuscript submissions: 5 May 2024 | Viewed by 129
Special Issue Editor
Interests: epilepsy; clinical neurophysiology; neurogenetics; brain imaging; epilepsy therapeutics; systems neuroscience; systems genetics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Epilepsy is among the most common neurological disorders. Childhood epilepsies are a heterogeneous group of conditions with differing diagnostic criteria, treatment, and prognosis. Epilepsy affects children and adolescents not only physically but also cognitively, behaviorally, and emotionally and significantly impairs their functionality. Meanwhile, epilepsy in childhood can vary in presentation and severity, requiring a multi-faceted approach to treatment. At present, non-pharmacologic and pharmacological interventions have been shown to improve seizure activity, curb disruptive behaviors, and improve social communication skills with varying degrees of success.
When people with epilepsy have seizures, they can be controlled well when provided with adequately selected therapy. Nevertheless, current medications still fail to eradicate seizures in 30–40% of patients (so-called pharmacoresistant epilepsy). Pharmacoresistant epilepsy can have a significant negative impact on patients’ quality of life, interfering with memory, cognition, comorbid depressive states, and anxiety disorders. Therefore, clinical research on childhood epilepsy still has a long way to go.
This Special Issue focuses on promoting the development of new and effective treatments for epilepsy in childhood and adolescence, encouraging submissions that address the current state of the art in epileptology and that indicate new areas for future research in the field.
Prof. Dr. Paul R. Carney
Guest Editor
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Keywords
- pediatric epilepsy
- clinical neurophysiology
- epilepsy genetics
- brain imaging
- neuropsychology
- epilepsy treatment
- neuromodulation
- epilepsy surgery
- ketogenic diet
- emergent treatments
- precision medicine
