Special Issue "Insight in the Application of Rehabilitation Devices in Neurological Disease"

A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neurotechnology and Neuroimaging".

Deadline for manuscript submissions: 25 April 2024 | Viewed by 1245

Special Issue Editor

Behavioral and Robotic Neurorehab Unit, IRCCS Centro Neurolesi “Bonino Pulejo”, 98123 Messina, Italy
Interests: neurorehabilitation; neuroscience; telemedicine; healthcare science

Special Issue Information

Dear Colleagues,

It is my pleasure to introduce a Special Issue of Brain Science dedicated to advances about the use of technological devices in neurorehabilitation.

Neurological diseases causing motor/cognitive impairments are among the most common causes of adult-onset disability. More than one billion of people are affected worldwide, and this number is expected to increase in upcoming years, because of the rapidly aging population.

Recent technological advances provide new tools for the development of novel and promising applications for neurological rehabilitation. To date, rehabilitation therapy can be aided by the technological support of robotic-based therapy, non-invasive brain stimulation, virtual reality, and telemedicine, to name a few. The ability to provide individualized treatment by designing tasks suited to the individual's cognitive and physical abilities increases the validity of interventions and supports adherence to therapy.

The purpose of this Special Issue is to bring together new literature to identify the contribution of technology-mediated neurorehabilitation, clarifying prospective research directions in the development of more autonomous rehabilitation processes. Both studies focusing on the process of neurorehabilitation through the use of technological devices (both clinical research and basic neuroscience) and studies discussing the challenges and opportunities for achieving more autonomous rehabilitation processes are included. Papers that explain the set of technical requirements that should be considered when designing and implementing autonomous robotic systems for rehabilitation are also welcome.

Research articles, short communications, letter to the editor, and review articles (narrative review, systematic review, and meta-analysis) are invited.

Dr. Maria Cristina De Cola
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • neurorehabilitation
  • virtual reality
  • brain-computer interface
  • robotic rehabilitation
  • technological devices design
  • neurological disorder
  • digital therapeutics
  • tele-neurorehabilitation
  • robot
  • brain stimulation

Published Papers (1 paper)

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12 pages, 729 KiB  
Assessing the Impact of Electrosuit Therapy on Cerebral Palsy: A Study on the Users’ Satisfaction and Potential Efficacy
Brain Sci. 2023, 13(10), 1491; https://doi.org/10.3390/brainsci13101491 - 22 Oct 2023
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The aim of this study is to evaluate the effectiveness of electrosuit therapy in the clinical treatment of children with Cerebral Palsy, focusing on the effect of the therapy on spasticity and trunk control. Moreover, the compliance of caregivers with respect to the [...] Read more.
The aim of this study is to evaluate the effectiveness of electrosuit therapy in the clinical treatment of children with Cerebral Palsy, focusing on the effect of the therapy on spasticity and trunk control. Moreover, the compliance of caregivers with respect to the use of the tool was investigated. During the period ranging from 2019 to 2022, a total of 26 children (18 M and 8 F), clinically stable and affected by CP and attending the Neurorehabilitation Unit of the “Padre Pio Foundation and Rehabilitation Centers”, were enrolled in this study. A subset of 12 patients bought or rented the device; thus, they received the administration of the EMS-based therapy for one month, whereas the others received only one-hour training to evaluate the feasibility (by the caregivers) and short-term effects. The Gross Motor Function Classification System was utilized to evaluate gross motor functions and to classify the study sample, while the MAS and the LSS were employed to assess the outcomes of the EMS-based therapy. Moreover, between 80% and 90% of the study sample were satisfied with the safety, ease of use, comfort, adjustment, and after-sales service. Following a single session of electrical stimulation with EMS, patients exhibited a statistically significant enhancement in trunk control. For those who continued this study, the subscale of the QUEST with the best score was adaptability (0.74 ± 0.85), followed by competence (0.67 ± 0.70) and self-esteem (0.59 ± 0.60). This study investigates the impact of the employment of the EMS on CP children’s ability to maintain trunk control. Specifically, after undergoing a single EMS session, LSS showed a discernible improvement in children’s trunk control. In addition, the QUEST and the PIADS questionnaires demonstrated a good acceptability and satisfaction of the garment by the patients and the caregivers. Full article
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