Neurodevelopmental and Neurodegenerative Disorders: Molecular Mechanisms and Therapeutic Strategies

A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Molecular and Cellular Neuroscience".

Deadline for manuscript submissions: 31 October 2024 | Viewed by 293

Special Issue Editors

E-Mail Website
Guest Editor
Singapore Nuclear Research and Safety Initiative, National University of Singapore, Singapore, Singapore
Interests: radiobiology; neurogenesis; neuroprotection

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Guest Editor
School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, China
Interests: epilepsy; hippocampus; epigenetics

Special Issue Information

Dear Colleagues,

With the advancement of modern neuroscience research techniques such as omics, including genomics, proteomics, metabolomics, metagenomics, phenomics, transcriptomics, single-cell RNA sequencing, connectomics, chemogenetics, optogenetics, machine learning and artificial intelligence, brain–computer interfaces (BCIs), computational modelling, functional magnetic resonance imaging (fMRI), and therapeutic strategies, staying current with the latest research and developments in the field of neurodevelopmental and neurodegenerative disorders may facilitate healthcare providers to use evidence-based approaches in their practice. For instance, based on an individual's unique genetic and molecular profile, scientists and clinicians may develop personalized treatment plans that are more effective and have fewer side effects, and public health policymakers may be able to achieve better allocation of resources, early intervention programs, and improved diagnostic and screening methods.

For this Special Issue of Brain Sciences entitled “Neurodevelopmental and Neurodegenerative Disorders: Molecular Mechanisms and Therapeutic Strategies", we welcome the submission of human, animal or cell experimental research work and review papers; our aim is to provide a platform to discuss the latest developments in research on neurodevelopmental and neurodegenerative disorders so as to facilitate researchers and healthcare providers to develop novel therapeutic approaches in their practice to improve the lives of patients.

Dr. Fengru Tang
Prof. Dr. Jianxin Liu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • neurodevelopmental and neurodegenerative disorders
  • molecular mechanisms
  • omics
  • therapeutic approaches

Published Papers

This special issue is now open for submission, see below for planned papers.

Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

Title: Morphological Evidence of Idebenone's Effects on Microglial Activation in MCAO Reperfusion Mice
Authors: Jian-Shui Zhang
Affiliation: School of Basic Medical Sciences, Xi’an Jiaotong University

Title: Inhibition of specificity protein 1 ameliorates anxiety-like behaviors through 5-HT1A receptor in mouse models of Parkinson's disease.
Authors: Lu Yao
Affiliation: School of Basic Medical Sciences, Xi’an Jiaotong University

Title: The Mechanism Underlying Phosphoinositide 3-kinase/protein kinase B Signaling Pathway Regulating RNA-binding motif protein 3, a Cold Shock Protein, to Protect Neural Stem Cells Induced by Mild Hypothermia
Authors: Qin-Dong Shi
Affiliation: The Second Affiliated Hospital, Xi'an Jiaotong University

Title: Alzheimer Disease and Type 2 Diabetes: focus on neuroglial cells
Authors: Adolfo Toledano; M Isabel Álvarez; Arantcha Rodríguez-Casado; Adolfo Toledano-Díaz
Affiliation: Instituto Cajal. CSIC, Inst Cajal, E-28002 Madrid, Spain

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