The Cerebellar Modulation for Affective and Social Functions: Novel Insights from Nonclinical and Clinical Conditions

A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Systems Neuroscience".

Deadline for manuscript submissions: closed (24 November 2023) | Viewed by 1889

Special Issue Editors


E-Mail Website
Guest Editor
1. Department of Psychology, Sapienza University of Rome, Via dei Marsi 78, 00185 Rome, Italy
2. Ataxia Laboratory, IRCCS Fondazione Santa Lucia, Via Ardeatina 306-354, 00179 Rome, Italy
Interests: cerebellum; cognition; MRI; neurodegenerative disease; autism; psychiatric disorders; tDCS

E-Mail Website
Guest Editor
1. Department of Psychology, Sapienza University of Rome, Via dei Marsi 78, 00185 Rome, Italy
2. Ataxia Laboratory, IRCCS Fondazione Santa Lucia, Via Ardeatina 306-354, 00179 Rome, Italy
Interests: cerebellum; cerebro-cerebellar connectivity; social cognition; cerebellar diseases; psychopathology

Special Issue Information

Dear Colleagues,

Novel findings and theories have arisen in recent decades about the starring role of the cerebellum in processing and optimizing widespread functions beyond motor control. Along a continuum from automatic to more sophisticated processes, the cerebellum integrates pivotal emotional information needed for humans to handle affective and social signs and to fulfill adaptive social behaviors. fMRI activation studies on healthy subjects have proven the recruitment of the cerebellum during emotional and social tasks execution. Additionally, clinical and neuroimaging findings on cerebellar diseases and neurodevelopmental and psychiatric conditions have revealed a cerebellar implication in social-affective domains. Further investigations of these aspects in neurotypical and pathological populations will lead to valuable knowledge for clinical practice and for the implementation of potential rehabilitation protocols.

This Special Issue aims to collect innovative contributions to deepen the understanding of the cerebellar role in modulating affective and social functions in nonclinical and clinical conditions, such as neurodevelopmental, neurodegenerative, and psychiatric disorders.

Topics may include:

- Brain imaging studies focused on the cerebellum and cerebro-cerebellar networks;

- Behavioral studies employing emotional/affective/social tools;

- Brain stimulation studies targeting the cerebellum;

- Studies integrating all the abovementioned techniques;

- Studies aiming at proposing the development of novel theories, experimental protocols and/or therapeutic practices.

Dr. Giusy Olivito
Dr. Libera Siciliano
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Brain Sciences is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cerebellum
  • cerebello-cerebral networks
  • emotion
  • affect
  • social cognition
  • neurodevelopment
  • neurodegeneration
  • psychiatric conditions
  • brain imaging
  • neuromodulation

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Review

16 pages, 1574 KiB  
Review
Cerebellum’s Contribution to Attention, Executive Functions and Timing: Psychophysiological Evidence from Event-Related Potentials
by Daniela Mannarelli, Caterina Pauletti, Paolo Missori, Carlo Trompetto, Filippo Cotellessa, Francesco Fattapposta and Antonio Currà
Brain Sci. 2023, 13(12), 1683; https://doi.org/10.3390/brainsci13121683 - 7 Dec 2023
Cited by 2 | Viewed by 1475
Abstract
Since 1998, when Schmahmann first proposed the concept of the “cognitive affective syndrome” that linked cerebellar damage to cognitive and emotional impairments, a substantial body of literature has emerged. Anatomical, neurophysiological, and functional neuroimaging data suggest that the cerebellum contributes to cognitive functions [...] Read more.
Since 1998, when Schmahmann first proposed the concept of the “cognitive affective syndrome” that linked cerebellar damage to cognitive and emotional impairments, a substantial body of literature has emerged. Anatomical, neurophysiological, and functional neuroimaging data suggest that the cerebellum contributes to cognitive functions through specific cerebral–cerebellar connections organized in a series of parallel loops. The aim of this paper is to review the current findings on the involvement of the cerebellum in selective cognitive functions, using a psychophysiological perspective with event-related potentials (ERPs), alone or in combination with non-invasive brain stimulation techniques. ERPs represent a very informative method of monitoring cognitive functioning online and have the potential to serve as valuable biomarkers of brain dysfunction that is undetected by other traditional clinical tools. This review will focus on the data on attention, executive functions, and time processing obtained in healthy subjects and patients with varying clinical conditions, thus confirming the role of ERPs in understanding the role of the cerebellum in cognition and exploring the potential diagnostic and therapeutic implications of ERP-based assessments in patients. Full article
Show Figures

Figure 1

Back to TopTop