Novel Plasmonic Biosensors

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensor and Bioelectronic Devices".

Deadline for manuscript submissions: closed (31 May 2021) | Viewed by 9146

Special Issue Editor


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Guest Editor
Department of Physics and Astronomy, Rice University, 6100 Main St, Houston, TX 77005, USA
Interests: plasmonics; metamaterials; nanophotonics; phase-change materials; nonlinear optics; biosensors; nanomedicine; reconfigurable antennae
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Special Issue Information

Dear Colleagues,

In a world of ever-increasing early-stage detection and treatment demand of devastating diseases (e.g., Alzheimer’s disease), recent advances in the use of plasmonic biosensors have proven that they are promising tools for better public health. Unlike other possible treatment modalities, such as chemotherapy, radiation therapy, and surgery, well-designed biosensing platforms based on optical signal transduction mechanisms, particularly the plasmonic biosensors as a counterpart of photonic biosensors, have the role of possessing innovative solutions as a bridge between biological/medical needs and sensing technologies. Within this framework, the transformative rise of plasmonic tools provides a potentially safer toolbox both at the cellular and molecular level by enabling high-throughput, label-free, quick, real-time, low-cost, high-specificity, and ultrasensitive detection.

Harnessing enhanced light-matter interactions through specialized building blocks, plasmonics technology has been getting involved in a new phase of biomedical and biochemical point-of-care analyses. From a more applied perspective, researchers are now able to tailor and produce next-generation plasmonic instruments for on-site theranostics and modern clinical applications, by improving their reliability, responsivity, and sensitivity one step further.

In this Special Issue of Biosensors, we seek the state-of-the-art research and development efforts in field of plasmonic biosensors. Both original article and review submissions are welcome.

Dr. Burak Gerislioglu
Guest Editor

Manuscript Submission Information

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Keywords

  • plasmonics
  • surface plasmon resonance (SPR)
  • optical biosensors
  • point-of-care
  • lab-on-a-chip
  • biophotonics
  • immunosensing
  • detection

Published Papers (2 papers)

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Research

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12 pages, 3669 KiB  
Article
Silver-Based SERS Pico-Molar Adenine Sensor
by Yonhua Tzeng and Bo-Yi Lin
Biosensors 2020, 10(9), 122; https://doi.org/10.3390/bios10090122 - 11 Sep 2020
Cited by 9 | Viewed by 3513
Abstract
Adenine is an important molecule for biomedical and agricultural research and applications. The detection of low concentration adenine molecules is thus desirable. Surface-enhanced Raman scattering (SERS) is a promising label-free detection and fingerprinting technique for molecules of significance. A novel SERS sensor made [...] Read more.
Adenine is an important molecule for biomedical and agricultural research and applications. The detection of low concentration adenine molecules is thus desirable. Surface-enhanced Raman scattering (SERS) is a promising label-free detection and fingerprinting technique for molecules of significance. A novel SERS sensor made of clusters of silver nanostructures deposited on copper bumps in valleys of an etched silicon substrate was previously reported to exhibit a low and reproducible detection limit for a 10−11 M neutral adenine aqueous solution. Reflection of laser illumination from the silicon surface surrounding a valley provides additional directions of laser excitation to adenine molecules adsorbing on a silver surface for the generation of enhanced SERS signal strength leading to a low detection limit. This paper further reports a concentration dependent shift of the ring-breathing mode SERS adenine peak towards 760 cm−1 with decreasing concentration and its pH-dependent SERS signal strength. For applications, where the pH value can vary, reproducible detection of 10−12 M adenine in a pH 9 aqueous solution is feasible, making the novel SERS structure a desirable pico-molar adenine sensor. Full article
(This article belongs to the Special Issue Novel Plasmonic Biosensors)
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Review

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15 pages, 4017 KiB  
Review
Plasmonic Sensors for Monitoring Biological and Chemical Threat Agents
by Yeşeren Saylan, Semra Akgönüllü and Adil Denizli
Biosensors 2020, 10(10), 142; https://doi.org/10.3390/bios10100142 - 15 Oct 2020
Cited by 34 | Viewed by 5187
Abstract
Sensors are excellent options owing to their ability to figure out a large number of problems and challenges in several areas, including homeland security, defense, medicine, pharmacology, industry, environment, agriculture, food safety, and so on. Plasmonic sensors are used as detection devices that [...] Read more.
Sensors are excellent options owing to their ability to figure out a large number of problems and challenges in several areas, including homeland security, defense, medicine, pharmacology, industry, environment, agriculture, food safety, and so on. Plasmonic sensors are used as detection devices that have important properties, such as rapid recognition, real-time analysis, no need labels, sensitive and selective sensing, portability, and, more importantly, simplicity in identifying target analytes. This review summarizes the state-of-art molecular recognition of biological and chemical threat agents. For this purpose, the principle of the plasmonic sensor is briefly explained and then the use of plasmonic sensors in the monitoring of a broad range of biological and chemical threat agents is extensively discussed with different types of threats according to the latest literature. A conclusion and future perspectives are added at the end of the review. Full article
(This article belongs to the Special Issue Novel Plasmonic Biosensors)
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