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Biosensors
Special Issues
Biosensors Applications for the Detection of Food Contaminants and Adulterants
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Biosensors Applications for the Detection of Food Contaminants and Adulterants

A special issue of Biosensors (ISSN 2079-6374).

Deadline for manuscript submissions: closed (15 December 2019) | Viewed by 19552

Special Issue Editor

Dr. Valérie Gaudin

E-Mail Website
Guest Editor
Anses-Laboratory of Fougeres, European Union Reference Laboratory (EU-RL) for Antimicrobial and Dye Residue Control in Food-Producing Animals, La Haute Marche-Javené, 35302 Fougères, France
Interests: biosensors; immunosensors; aptasensors; optical and electrochemical biosensors; animal derived-food products; veterinary drug residues; antimicrobial residues
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Food chemical or microbiological (e.g., Listeria) contaminants are any substance not intentionally added to food, while food adulterants (e.g., melamine) are intentionally added. The origins of contamination are multiple: naturally occurring contaminants, environmental pollution (e.g., industrial activities), veterinary treatments, extensive agriculture (e.g., pesticides), packaging migration, food transformation, and disinfection. Contaminated and adulterated food can have harmful effects on human safety (e.g., allergies, toxicity, antimicrobial resistance, and the endocrine disruptor effect). The detection principles of conventional screening methods are microbiological, immunological (e.g., ELISA tests), instrumental physico-chemical, and PCR methods. Following the promising progress of biosensors for medical diagnostics (e.g., point of care (POC) testing), biosensors for food applications allow the development of sensitive, selective, quick, robust, and cheap screening methods to control food products: This Special Issue will present innovative applications of biosensors (e.g., optical, electrochemical, and mass sensitive) for the detection of contaminants and adulterants in foodstuffs of animal and plant origin. The first objective of this Special issue is to highlight the benefits of biosensors that could make them the screening tool for food contaminants of tomorrow. This Special Issue also aims to show the promising contribution of innovative biosensing elements (e.g., aptamers, molecular imprinting polymer (MIP), DNA), nanomaterials, and new technologies (e.g., micro/nanofluidics, Internet of Things (IoT)) to the development of more sensitive, portable, robust and cheaper biosensors. Review and research papers are welcome.

Dr. Valérie Gaudin
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Detection
  • Screening
  • Contaminants
  • Adulterants
  • Food
  • Biosensor
  • Optical
  • Electrochemical
  • Mass sensitive
  • Nanomaterials
  • Aptamers
  • Molecular imprinting polymer (MIP)
  • DNA
  • Micro/Nanofluidics
  • Internet of Things (IoT)

Published Papers (3 papers)

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Research

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15 pages, 1800 KiB  
Article
Detection of Salmonella Typhimurium in Romaine Lettuce Using a Surface Plasmon Resonance Biosensor
by Devendra Bhandari, Fur-Chi Chen and Roger C. Bridgman
Biosensors 2019, 9(3), 94; https://doi.org/10.3390/bios9030094 - 28 Jul 2019
Cited by 36 | Viewed by 7105
Abstract
Leafy vegetables have been associated with high-profile outbreaks causing severe illnesses. Timely and accurate identification of potential contamination is essential to ensure food safety. A surface plasmon resonance (SPR) assay has been developed for the detection of Salmonella Typhimurium in leafy vegetables. The [...] Read more.
Leafy vegetables have been associated with high-profile outbreaks causing severe illnesses. Timely and accurate identification of potential contamination is essential to ensure food safety. A surface plasmon resonance (SPR) assay has been developed for the detection of Salmonella Typhimurium in leafy vegetables. The assay utilizes a pair of well characterized monoclonal antibodies specific to the flagellin of S. Typhimurium. Samples of romaine lettuce contaminated with S. Typhimurium at different levels (between 0.9 and 5.9 log cfu/g) were pre-enriched in buffered peptone water. Three SPR assay formats, direct assay, sequential two-step sandwich assay, and pre-incubation one-step sandwich assay were evaluated. All three assay formats detect well even at a low level of contamination (0.9 log cfu/g). The SPR assay showed a high specificity for the detection of S. Typhimurium in the presence of other commensal bacteria in the romaine lettuce samples. The results also suggested that further purification of flagellin from the sample preparation using immunomagnetic separation did not improve the detection sensitivity of the SPR assay. The functional protocol developed in this study can be readily used for the detection of S. Typhimurium in leafy vegetables with high sensitivity and specificity. Full article
(This article belongs to the Special Issue Biosensors Applications for the Detection of Food Contaminants and Adulterants)
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Review

Jump to: Research

38 pages, 24603 KiB  
Review
The Growing Interest in Development of Innovative Optical Aptasensors for the Detection of Antimicrobial Residues in Food Products
by Valérie Gaudin
Biosensors 2020, 10(3), 21; https://doi.org/10.3390/bios10030021 - 03 Mar 2020
Cited by 15 | Viewed by 5452
Abstract
The presence of antimicrobial residues in food-producing animals can lead to harmful effects on the consumer (e.g., allergies, antimicrobial resistance, toxicological effects) and cause issues in food transformation (i.e., cheese, yogurts production). Therefore, to control antimicrobial residues in food products of animal origin, [...] Read more.
The presence of antimicrobial residues in food-producing animals can lead to harmful effects on the consumer (e.g., allergies, antimicrobial resistance, toxicological effects) and cause issues in food transformation (i.e., cheese, yogurts production). Therefore, to control antimicrobial residues in food products of animal origin, screening methods are of utmost importance. Microbiological and immunological methods (e.g., ELISA, dipsticks) are conventional screening methods. Biosensors are an innovative solution for the development of more performant screening methods. Among the different kinds of biosensing elements (e.g., antibodies, aptamers, molecularly imprinted polymers (MIP), enzymes), aptamers for targeting antimicrobial residues are in continuous development since 2000. Therefore, this review has highlighted recent advances in the development of aptasensors, which present multiple advantages over immunosensors. Most of the aptasensors described in the literature for the detection of antimicrobial residues in animal-derived food products are either optical or electrochemical sensors. In this review, I have focused on optical aptasensors and showed how nanotechnologies (nanomaterials, micro/nanofluidics, and signal amplification techniques) largely contribute to the improvement of their performance (sensitivity, specificity, miniaturization, portability). Finally, I have explored different techniques to develop multiplex screening methods. Multiplex screening methods are necessary for the wide spectrum detection of antimicrobials authorized for animal treatment (i.e., having maximum residue limits). Full article
(This article belongs to the Special Issue Biosensors Applications for the Detection of Food Contaminants and Adulterants)
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22 pages, 5191 KiB  
Review
Cutting-Edge Advances in Electrochemical Affinity Biosensing at Different Molecular Level of Emerging Food Allergens and Adulterants
by Susana Campuzano, Víctor Ruiz-Valdepeñas Montiel, Verónica Serafín, Paloma Yáñez-Sedeño and José Manuel Pingarrón
Biosensors 2020, 10(2), 10; https://doi.org/10.3390/bios10020010 - 06 Feb 2020
Cited by 28 | Viewed by 6175
Abstract
The presence of allergens and adulterants in food, which represents a real threat to sensitized people and a loss of consumer confidence, is one of the main current problems facing society. The detection of allergens and adulterants in food, mainly at the genetic [...] Read more.
The presence of allergens and adulterants in food, which represents a real threat to sensitized people and a loss of consumer confidence, is one of the main current problems facing society. The detection of allergens and adulterants in food, mainly at the genetic level (characteristic fragments of genes that encode their expression) or at functional level (protein biomarkers) is a complex task due to the natural interference of the matrix and the low concentration at which they are present. Methods for the analysis of allergens are mainly divided into immunological and deoxyribonucleic acid (DNA)-based assays. In recent years, electrochemical affinity biosensors, including immunosensors and biosensors based on synthetic sequences of DNA or ribonucleic acid (RNA), linear, aptameric, peptide or switch-based probes, are gaining special importance in this field because they have proved to be competitive with the methods commonly used in terms of simplicity, test time and applicability in different environments. These unique features make them highly promising analytical tools for routine determination of allergens and food adulterations at the point of care. This review article discusses the most significant trends and developments in electrochemical affinity biosensing in this field over the past two years as well as the challenges and future prospects for this technology. Full article
(This article belongs to the Special Issue Biosensors Applications for the Detection of Food Contaminants and Adulterants)
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