Chemo/Biosensing for Biosignal Processing and Amplification

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensors and Healthcare".

Deadline for manuscript submissions: 30 June 2024 | Viewed by 1299

Special Issue Editors


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Guest Editor
1. Hangzhou Institute of Medicine, Chinese Academy of Sciences, Hangzhou 310022, China
2. College of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, China
Interests: intelligent biosensors; bioanalytical chemistry; molecular medicine

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Guest Editor
Hangzhou Institute of Medicine, Chinese Academy of Sciences, Hangzhou 310022, China
Interests: molecular diagnosis; molecular medicine; DNA nanotechnology

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Guest Editor
College of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, China
Interests: biosensing; theranostic nanomedicine; medicinal chemical biology

Special Issue Information

Dear Colleagues,

Biosensors are analytical tools or systems consisting of immobilized biosensitive materials as recognition elements (including enzymes, antibodies, antigens, microorganisms, cells, tissues, nucleic acids and other biologically active substances), appropriate physicochemical transducers and efficient signal amplification strategies. Currently, the latest advances in nanoscience, molecular biology and molecular medicine have placed higher demands on the development of intelligent biosensors. On the one hand, intelligent biosensors support molecular engineering technology as a means to diversify and make their functions intelligent by designing and building devices with logical computing functions, which are applied to solve difficult problems in biomedicine such as life analysis and molecular diagnosis of diseases. On the other hand, the identification and enrichment of target biomolecules are optimized for detection, and the detection signal of the sensor interface is purposefully amplified through signal amplification technology. This Special Issue aims, therefore, to cover the developments in chemo/biosensing for biosignal processing and amplification technologies and their applications in related fields. We kindly invite a wide range of original research and review articles, including, but not limited to, the following topics: analytical chemistry, bioanalytical chemistry, biomedicine, precision diagnostics, pharmaceutical analysis, and environmental monitoring research.

Prof. Dr. Fengli Qu
Dr. Jin Li
Dr. Yan Zhao
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • intelligent biosensors
  • biosensing technology
  • bio-signal processing
  • signal amplification
  • aptamer
  • biomolecular markers
  • molecular medicine
  • bioanalytical chemistry

Published Papers (1 paper)

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Research

11 pages, 4007 KiB  
Article
One-Step Ultrasonic Preparation of Stable Bovine Serum Albumin-Perovskite for Fluorescence Analysis of L-Ascorbic Acid and Alkaline Phosphatase
by Lei Deng, Feng Huang, Aomei Zhang, Tingting Wang, Minghui Yang, Xiaoqing Li and Xiang Chen
Biosensors 2023, 13(8), 770; https://doi.org/10.3390/bios13080770 - 28 Jul 2023
Cited by 2 | Viewed by 902
Abstract
Halide lead perovskite has attracted increased attention due to its excellent optical properties. However, the poor stability of the halide lead perovskite nanocrystals has been a major obstacle to their application in biosensing. Here, we proposed a method to synthesize CsPbBr3/BSA [...] Read more.
Halide lead perovskite has attracted increased attention due to its excellent optical properties. However, the poor stability of the halide lead perovskite nanocrystals has been a major obstacle to their application in biosensing. Here, we proposed a method to synthesize CsPbBr3/BSA NCs perovskite using bovine serum albumin (BSA) as a zwitterion ligand. Then, a fluorescent sensor for alkaline phosphatase determination based on CsPbBr3/BSA NCs was successfully built via the interaction of L-ascorbic acid (AA) with BSA on the perovskite surface. Under optimal conditions, the sensor showed a linear concentration range from 50 to 500 μM with a detection limit of 28 μM (signal-to-noise ratio of 3) for AA, and demonstrated a linear concentration range from 40 to 500 U/L with a detection limit of 15.5 U/L (signal-to-noise ratio of 3) for alkaline phosphatase (ALP). In addition, the proposed fluorescent biosensor exhibited good selectivity and recovery in the determination of ALP in human serum. This strategy offers an innovative way for enhancing the water stability of lead halide perovskite and promoting their application in biosensing areas. Full article
(This article belongs to the Special Issue Chemo/Biosensing for Biosignal Processing and Amplification)
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