Emerging Surface-Enhanced Raman Scattering Strategies and Applications for Biosensors
A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Optical and Photonic Biosensors".
Deadline for manuscript submissions: 31 July 2024 | Viewed by 101
Special Issue Editors
Interests: Raman spectral electrochemistry; chemical imaging; chemical sensors and biosensors; SERS-probes for POCT applications
Special Issues, Collections and Topics in MDPI journals
Interests: chiral inorganic nanomaterials; surface-enhanced Raman scattering; chiroptical analysis; chiral discrimination
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Surface-enhanced Raman scattering (SERS) has been recognized as a sensitive and rapid tool used to provide rich vibrational spectroscopic information. However, there are still many issues that restrict the real application of SERS, especially in biosensing. For example, although various SERS substrates have been reported, the stability and reproducibility of substrates are concerning. To detect complex samples or those biomolecules with low-level Raman scattering cross-sections, it is challenging to realize molecule specificity and a high sensitivity. In addition, novel materials have been explored to construct SERS substrates, of which, the SERS mechanism remains to be clarified. In recent years, many efforts have been made to explore new applications of SERS in various bio-related areas (e.g., biological sample analysis, disease diagnosis, and nano–bio interactions) and achieve a high resolution in biological samples. Simultaneously, modern data processing methods (e.g., machine learning and algorithms) are also employed for SERS data analysis.
Over 40 years have passed since the discovery of SERS. Challenges and opportunities co-exist in the development of SERS techniques. Therefore, this Special Issue focuses on the emerging SERS strategies and applications in biosensing. The topics of this issue include, but are not limited to:
- The SERS analysis of biomolecules, biomarkers, bio-related exogenous species (e.g., drugs, pesticide, and cosmetic ingredients), biological samples, and bio–nano interactions;
- Novel SERS substrates for biosensing;
- The reliable and reproducible preparation of SERS biosensors;
- SERS strategies with improved selectivity and sensitivity for complex biological samples;
- SERS imaging in biological samples;
- SERS data processing methods;
- Portable SERS biosensing devices.
Prof. Dr. Haifeng Yang
Dr. Xinling Liu
Guest Editors
Manuscript Submission Information
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Keywords
- SERS
- biosensors
- SERS imaging
- biomarkers
- disease diagnosis
