Special Issue "Biosensors for the Analysis and Detection of Drug, Food or Disease"

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Biosensors and Healthcare".

Deadline for manuscript submissions: 29 February 2024 | Viewed by 894

Special Issue Editors

Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China.
Interests: novel diagnostic technologies for human diseases; food and environmental safety
Dr. Junhua Chen
E-Mail Website
Guest Editor
Guangdong Institute of Eco-Environment and Soil Science, Guangzhou, China
Interests: environmental quality and food safety

Special Issue Information

Dear Colleagues,

Burgeoning biosensor technology offers an excellent analytical platform for the rapid, low-cost, portable, and on-site detection of various analytes. Using bioreceptors as the molecular recognition elements, biosensors can recognize a specific analyte based on different mechanisms, such as aptamer-target binding, nucleic acid hybridization, antigen-antibody recognition, enzyme inhibition, and enzyme-mimicking activity. There are many hazardous substances in drug, food, environmental, and biological samples, such as heavy metals, mycotoxins, pesticides, food-borne pathogens, narcotic drugs, veterinary drugs, illegal additives, persistent organic pollutants, and biomarkers of infectious diseases. In recent years, some exquisite biosensors have been developed for the detection of these analytes, including fluorescent, electrochemical, colorimetric, electrochemiluminescent, and lateral flow strip methods. The challenge is how to improve the detection sensitivity and specificity when confronted with complex practical samples. At the same time, on-site analysis has attracted more and more attention in recent years, since it can provide qualitative or/and quantitative information of samples. The realization of on-site analysis largely depends on instruments and sample preparation technologies. Thus, the development of portable instruments for on-site analysis of contaminants in real samples is highly desirable.

This Special Issue is soliciting original articles and reviews on “Biosensors for the Analysis and Detection of Drug, Food or Disease”, mainly focusing on novel analytical methods, biosensors, and portable instruments for the detection of contaminants and biomarkers in drug, food, environmental, and biological samples. We would like to invite you to submit your manuscript to us.

Prof. Dr. Lingwen Zeng
Dr. Junhua Chen
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biosensor
  • heavy metal
  • mycotoxin
  • pesticide
  • biomarker
  • drug
  • aptamer
  • rapid detection
  • on-site analysis
  • portable instrument

Published Papers (1 paper)

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Research

13 pages, 2662 KiB  
Article
The Development of Reagentless Amperometric Glucose Biosensor Based on Gold Nanostructures, Prussian Blue and Glucose Oxidase
Biosensors 2023, 13(10), 942; https://doi.org/10.3390/bios13100942 - 20 Oct 2023
Viewed by 733
Abstract
Precise blood glucose detection plays a crucial role in diagnosing and medicating diabetes, in addition to aiding diabetic patients in effectively managing their condition. In this research, a first-generation reagentless amperometric glucose biosensor was developed by combining the graphite rod (GR) electrode modification [...] Read more.
Precise blood glucose detection plays a crucial role in diagnosing and medicating diabetes, in addition to aiding diabetic patients in effectively managing their condition. In this research, a first-generation reagentless amperometric glucose biosensor was developed by combining the graphite rod (GR) electrode modification by gold nanostructures (AuNS) and Prussian blue (PB) with glucose oxidase (GOx)—an enzyme that can oxidize glucose and produce H2O2. Firstly, AuNS was electrochemically deposited on the GR electrode (AuNS/GR), and then PB was electrochemically synthesized on the AuNS/GR electrode (PB/AuNS/GR). Finally, GOx was immobilized over the PB/AuNS nanocomposite with the assistance of Nafion (Nf) (Nf-GOx/PB/AuNS/GR). An application of PB in the design of a glucose biosensor enables an easy electrochemical reduction and, thus, the determination of the H2O2 produced during the GOx-catalyzed oxidation of glucose in the sample at a low operation potential of −0.05 V vs. Ag/AgCl/KCl3 mol L−1. In addition, AuNS increased the electrochemically active surface area, improved the GOx immobilization and ensured a higher analytical signal. The developed glucose biosensor based on the Nf-GOx/PB/AuNS/GR electrode exhibited a wide linear range, from 0.025 to 1 mmol L−1 of glucose, with a 0.0088 mmol L−1 limit of detection, good repeatability and high selectivity over electroactive interfering substances. The developed biosensor is convenient for the determination of glucose in the physiological environment. Full article
(This article belongs to the Special Issue Biosensors for the Analysis and Detection of Drug, Food or Disease)
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