Special Issue "Genetics, Obesity, Diabetes and Metabolic Syndrome"

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Endocrinology and Metabolism Research".

Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 189

Special Issue Editor

Dr. Guanglin Zhang
E-Mail Website
Guest Editor
Division of Life Sciences, University of California, Los Angeles, Los Angeles, CA, USA
Interests: metabolic syndrome; microbiome; next-generation sequencing; neurodegenerative diseases
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Obesity, diabetes, and metabolic syndrome are interconnected conditions that influenced by multiple factors, including genetic, environmental, and lifestyle factors. Each condition has both unique genetic components and genetic mechanisms that contribute to their development. Genetics play a significant role in determining an individual’s susceptibility to obesity and type 2 diabetes. Certain genetic variations can influence factors, such as metabolism, appetite regulation, fat storage, and insulin sensitivity.

Obesity is closely linked to the development of type 2 diabetes. Excess body fat, particularly abdominal fat, can contribute to the development of type 2 diabetes. Additionally, shared genetic factors can contribute to both obesity and insulin resistance, further connecting the two conditions. Both obesity and type 2 diabetes involve metabolic dysfunction. In obesity, there is often an imbalance between energy intake and expenditure, leading to the excess accumulation of fat and disruptions in metabolic processes. Similarly, type 2 diabetes is characterized by impaired glucose metabolism, insulin resistance, and the dysregulation of various metabolic pathways. These metabolic dysfunctions contribute to the development and progression of both conditions.

Understanding the connections among genetic factors, obesity, diabetes, and metabolic dysfunction is important for identifying individuals at higher risk, developing preventive strategies, and tailoring personalized interventions for the better management of these conditions.

This Special Issue aims to present cutting-edge research and comprehensive reviews that provide the most updated explanations of topics concerning metabolic diseases:

  1. The identification of genetic markers associated with obesity, type 2 diabetes, and metabolic dysfunction;
  2. Molecular and biochemical mechanisms underlying metabolic diseases;
  3. Novel natural approaches for the potential prevention and therapeutic strategies of obesity, diabetes, and related conditions;
  4. Multiomics used to study metabolic diseases.

Dr. Guanglin Zhang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • obesity
  • diabetes
  • metabolic syndrome
  • metabolic diseases
  • genomics
  • multiomics
  • RNAseq
  • single-cell sequencing
  • GWAS
  • metabolomics

Published Papers

There is no accepted submissions to this special issue at this moment.
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