Special Issue "Genetics, Obesity, Diabetes and Metabolic Syndrome"
Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 189
Interests: metabolic syndrome; microbiome; next-generation sequencing; neurodegenerative diseases
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Obesity, diabetes, and metabolic syndrome are interconnected conditions that influenced by multiple factors, including genetic, environmental, and lifestyle factors. Each condition has both unique genetic components and genetic mechanisms that contribute to their development. Genetics play a significant role in determining an individual’s susceptibility to obesity and type 2 diabetes. Certain genetic variations can influence factors, such as metabolism, appetite regulation, fat storage, and insulin sensitivity.
Obesity is closely linked to the development of type 2 diabetes. Excess body fat, particularly abdominal fat, can contribute to the development of type 2 diabetes. Additionally, shared genetic factors can contribute to both obesity and insulin resistance, further connecting the two conditions. Both obesity and type 2 diabetes involve metabolic dysfunction. In obesity, there is often an imbalance between energy intake and expenditure, leading to the excess accumulation of fat and disruptions in metabolic processes. Similarly, type 2 diabetes is characterized by impaired glucose metabolism, insulin resistance, and the dysregulation of various metabolic pathways. These metabolic dysfunctions contribute to the development and progression of both conditions.
Understanding the connections among genetic factors, obesity, diabetes, and metabolic dysfunction is important for identifying individuals at higher risk, developing preventive strategies, and tailoring personalized interventions for the better management of these conditions.
This Special Issue aims to present cutting-edge research and comprehensive reviews that provide the most updated explanations of topics concerning metabolic diseases:
- The identification of genetic markers associated with obesity, type 2 diabetes, and metabolic dysfunction;
- Molecular and biochemical mechanisms underlying metabolic diseases;
- Novel natural approaches for the potential prevention and therapeutic strategies of obesity, diabetes, and related conditions;
- Multiomics used to study metabolic diseases.
Dr. Guanglin Zhang
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- metabolic syndrome
- metabolic diseases
- single-cell sequencing