Innate Immune Responses in Virus Infection
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Immunology and Immunotherapy".
Deadline for manuscript submissions: closed (31 May 2023) | Viewed by 3091
Special Issue Editor
Special Issue Information
Dear Colleagues,
The innate immune response to viral infection encompasses a wide range of mechanisms of body cells and tissues that limit the establishment of viral infection, viral replication, and spread. Innate immunity is also a major driver of the adaptive immune response. The innate immune system includes the antiviral response of infected cells, their recognition by effector cells, mechanisms to eliminate damaged cells, and the inflammatory response. Many viruses have evolved various mechanisms to evade the host's innate immune response, including interference with metabolic pathways, inflammasomes, autophagy, and apoptosis. These strategies are a critical basis for their virulence and cell tropism. The innate immune response to viruses, therefore, involves not only the study of classical effector mechanisms, such as natural killer cells or type I interferon-induced antiviral states, but also a broad spectrum of cell and tissue functions. The tremendous progress in understanding the physiology of cellular processes makes it necessary to also look at them from the perspective of innate immunity to viruses and to continuously upgrade innate immune functions. This Special Issue focuses on compiling a wide range of research and review articles that can reveal new aspects and advances in understanding the mechanisms of innate immune responses to various viruses. The articles that potentially define novel targets for antiviral therapies are especially welcomed.
Prof. Dr. Pero Lučin
Guest Editor
Manuscript Submission Information
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