Adiponectin and Its Receptor Interactions in Human Disease

A special issue of Biomedicines (ISSN 2227-9059).

Deadline for manuscript submissions: closed (28 February 2018) | Viewed by 6658

Special Issue Editor


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Guest Editor
Molecular and Cell Biology, College of Public Health, Medical & Veterinary Sciences, and Australian Institute for Tropical Health and Medicine, James Cook University, Townsville, QLD 4811, Australia
Interests: metabolism; liver cancer; targeting liver fibrosis

Special Issue Information

Dear Colleagues,

This Special Issue will focus on “Adiponectin and Its Receptor Interactions in Human Disease”.

Adiponectin is the most abundant adipocytokine. Through its receptors, it can mediate a variety of protective actions in various organs. Significantly, with increased adiposity, serum adiponectin levels fall and dysregulated inflammation and metabolism can ensue, and manifest as human disease. There is intense interest in targeting increases in adiponectin levels and signaling to alleviate disease.

Thus, for this Special Issue, we cordially invite authors in the field to submit original research or review articles pertaining to this important and fast-progressing field of biomedicine.

Dr. Lionel  Hebbard
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Liver disease
  • NASH
  • NAFLD
  • Fatty acid metabolism
  • Glucose utilization
  • Hepatic inflammation
  • Cardiac disease
  • Cancer signaling
  • Metabolic function
  • Receptor Biology
  • Vascular function

Published Papers (1 paper)

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Review

16 pages, 850 KiB  
Review
Adiponectin Signaling Pathways in Liver Diseases
by Tania Gamberi, Francesca Magherini, Alessandra Modesti and Tania Fiaschi
Biomedicines 2018, 6(2), 52; https://doi.org/10.3390/biomedicines6020052 - 07 May 2018
Cited by 58 | Viewed by 6280
Abstract
In the liver, adiponectin regulates both glucose and lipid metabolism and exerts an insulin-sensitizing effect. The binding of adiponectin with its specific receptors induces the activation of a proper signaling cascade that becomes altered in liver pathologies. This review describes the different signaling [...] Read more.
In the liver, adiponectin regulates both glucose and lipid metabolism and exerts an insulin-sensitizing effect. The binding of adiponectin with its specific receptors induces the activation of a proper signaling cascade that becomes altered in liver pathologies. This review describes the different signaling pathways in healthy and diseased hepatocytes, also highlighting the beneficial role of adiponectin in autophagy activation and hepatic regeneration. Full article
(This article belongs to the Special Issue Adiponectin and Its Receptor Interactions in Human Disease)
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