Thyroid Nodule: Updates on the Molecular Mechanism and Diagnosis
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".
Deadline for manuscript submissions: 31 December 2024 | Viewed by 2187
Special Issue Editor
Special Issue Information
Dear Colleagues,
The Special Issue "Thyroid Nodule: Updates on the Molecular Mechanism and Diagnosis" focuses on the growing importance of characterizing thyroid nodules with maximum accuracy.
The accuracy certainly derives from the knowledge of the molecular mechanisms underlying formation of thyroid nodules and from the use of more precise diagnostic tools.
The incidence of thyroid cancer is increasing rapidly worldwide, although its mortality rate remains flat. Thyroid nodules occur commonly in the general population, mostly as incidental findings at ultrasound evaluation, which is the first examination method used for neck imaging. However, although ultrasound is an established and very sensitive method for detecting thyroid nodules, and superior to clinical physical palpation, it has a relatively low diagnostic performance when it comes to differentiating between benign and malignant nodules.
In recent years, several studies have proposed the potential use of new ultrasound techniques through a multiparametric evaluation by using new methods, such as CEUS (contrast-enhanced ultrasound) and, especially, USE (US elastography) to increase the accuracy of baseline ultrasound. This is used in order to improve the non-invasive diagnostic power of thyroid nodules, avoiding invasive investigations, such as feed needle aspiration cytology (FNAC) or biopsy, which are often necessary.
The purpose of this Special Issue is to analyze the molecular mechanisms underlying the formation of thyroid nodules and to take stock of the updates present in the most recent literature regarding a more precise instrumental diagnosis, combining new experiments.
Dr. Emanuele David
Guest Editor
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