Recent Advances in Gastrointestinal Cancers: From Microbiota Modulation to New Therapeutic Approaches
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cancer Biology and Oncology".
Deadline for manuscript submissions: 30 September 2024 | Viewed by 67
Special Issue Editors
Interests: oncology; metastasis; cell cultures; 3D models; cancer organoids; microbiota
Special Issues, Collections and Topics in MDPI journals
Interests: microbiome; immunology; gastrointestinal cancers; nutrition; gut-brain axis; neurodegeneration; neuroinflammation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Malignant tumors that affect the gastrointestinal tract, known as gastrointestinal (GI) cancers, are widespread. Globally, GI cancers are estimated to be responsible for one in four cancer cases and one in three deaths. This Special Issue aims to elucidate potential areas of progress in the field of GI cancers, including the modulation of the microbiota and novel therapeutic approaches.
Research areas may include (but are not limited to) the following:
- Modulation of the microbiota: role of the gut microbiome in influencing GI cancer development and response to treatment; manipulation of the microbiota through interventions such as probiotics, prebiotics, and fecal microbiota transplantation; and methods of modulating the microbiome to enhance response to immunotherapies, such as checkpoint inhibitors.
- Immunotherapy: efficacy of checkpoint inhibitors, such as pembrolizumab and nivolumab, in various GI malignancies and the exploration of CAR-T potential in GI cancers.
- Precision medicine: advances in molecular profiling and genomics, leading to the identification of specific biomarkers associated with GI cancers, and the development of liquid biopsy techniques for monitoring GI cancers.
- Targeted therapies: identify additional targeted therapies for specific subtypes of GI cancers in addition to HER2 therapies.
- Artificial intelligence in diagnostics: evaluation of machine learning algorithms to analyze medical images and to predict the prognosis and disease outcomes of GI cancers.
Dr. Serena Martinelli
Dr. Elena Niccolai
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- gastrointestinal cancers
- microbiota
- anticancer therapy
- immunotherapy
- precision medicine
