Special Issue "Aortic Aneurysms: Vascular Remodeling and Repair"
Deadline for manuscript submissions: closed (31 August 2022) | Viewed by 25773
A printed edition of this Special Issue is available here.
Interests: vascular remodelling; Renin-Angiotensin-Aldosterone system; extracellular matrix; proteolysis; matrix metalloproteinases; aneurysm
Special Issues, Collections and Topics in MDPI journals
Aortic aneurysm is a multifactorial disease that is characterized by vascular remodeling due to degradation of the extracellular matrix and reduced vascular repair. It is commonly associated with atherosclerosis, hypertension, and thrombotic disorders. Our understanding of the pathogenesis of aneurysm has significantly increased over the last few decades, with data pointing to the roles of genetics, hemodynamics, inflammation, and immune response. Nevertheless, no pharmacotherapy is available to date. Present treatment options are restricted to surgical interventions such as endovascular stents or open surgical procedures that are not appropriate for all patients. Thus, there is a need for specific and effective new treatments that prevent aneurysmal growth, reduce the risk of rupture, and prevent aneurysmal extension after surgical repair. New discoveries in the field of translational biology, cell therapy, and regenerative medicine, together with new approaches to experimental design and target drug release, should accelerate the development of new therapies.This Special Issue invites both original manuscripts that describe novel findings and cutting-edge review articles that illustrate recent advances in molecular and cell biology, pathophysiology, biomarkers, novel non-surgical medications, and targeted drug delivery for aortic aneurysm.
Dr. Elena Kaschina
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- aortic aneurysm
- pharmacological therapy
- experimental model
- drug delivery