Antioxidants and Oxidative Stress in Human Health and Diseases
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".
Deadline for manuscript submissions: 30 April 2024 | Viewed by 888
Special Issue Editor
Interests: oxidative stress; inflammation; autophagy; metabolic disease; neurodegenerative disease; atheroslcerosis; preclinical pharmacology; natural products; flavonoids; cannabinoids; adenosine signaling
Special Issue Information
Dear Colleagues,
Oxidative stress is caused by an imbalance between the accumulation of oxygen reactive species (ROS), such as superoxide radicals (O2•−), hydrogen peroxide (H2O2), hydroxyl radicals (•OH), and singlet oxygen (1O2), and the ability to neutralize them. The accumulation of ROS causes cellular damage to the metabolism, negatively affecting several cellular structures and molecules, such as DNA, lipids, proteins; this accumulation can trigger cell inflammation, apoptosis and necrosis, peroxidation and damage of lipoproteins and membranes, DNA damage and chromosomal aberration, damage of collagen structure and mitochondrial function. Indeed, oxidative stress is involved in the initiation and progression of several diseases, such as cancer, cardiovascular disease, neurological disease, rheumatoid arthritis and autoimmune diseases. Moreover, recent studies demonstrated that the accumulation of ROS causes infertility in males and females, damaging the reproductive system. New therapeutic approaches targeting oxidative stress and its signaling molecules could provide hopeful benefits to treat several human diseases.
The purpose of this Special Issue of Biomedicines “Antioxidants and Oxidative Stress in Human Health and Diseases” is to include original research papers and/or relevant updates of literature data on the new insights into the pathogenesis, molecular pathways and the beneficial effects of novel and safe treatments of oxidative stress associated with several human diseases.
Dr. Federica Mannino
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- oxidative stress
- inflammation
- human diseases
- apoptosis
- peroxidation
- DNA damage
- mitochondria
