Pluripotent Stem Cell Biology and Engineering
A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Regenerative Engineering".
Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 6357
Special Issue Editors
2. Associate Laboratory i4HB - Institute for Health and Bioeconomy at Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa, Portugal
Interests: human pluripotent stem cells; 3D cell culture; cell expansion; organoids; drug screening; toxicity assessment; scale up; organ-on-a-chip; body-on-a-chip
2. Associate Laboratory i4HB - Institute for Health and Bioeconomy at Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa, Portugal 3. Regenerative Medicine and Cellular Therapies, School of Pharmacy, University of Nottingham, University Park, NG7 2RD, UK
Interests: bioelectronics; biomaterials; additive manufacturing; bioprinting
Special Issue Information
Dear Colleagues,
Pluripotent stem cells have proven to be powerful tools in bioengineering due to their enormous potential regarding disease modelling, drug discovery and cell therapy. Strategies towards a more efficient and reliable recapitulation of embryonic development are still required, and this can be achieved through further study of pluripotency mechanisms and methods to direct pluripotent stem cells towards a specific fate.
By carefully controlling the culture microenvironment, either using biochemical or biophysical cues, in combination with different bioengineering approaches, either at a cellular, multicellular, and multiorgan levels, it will be possible to fully comprehend and recreate the embryonic development, accelerating the discovery of novel applications and strategies for human pluripotent stem cells and their derivatives. This includes high-throughput screening for efficient and personalized new drugs, platforms that provide a better understanding of disease mechanisms or even the development of robust cell therapy products.
This Special Issue aims to gather articles that highlight new possibilities towards Pluripotent Stem Cell Biology and Engineering, from cellular and biomaterial perspectives. We are welcoming original research articles, review articles and short communications.
Potential topics in this Special Issue include, but are not limited to, the following:
- New tissue engineering strategies;
- Genome editing of human pluripotent stem cells;
- Disease modeling using human pluripotent stem cells;
- Microenvironment control strategies;
- Bioprinted cell-based models;
- Biomimetic scaffold development;
- Novel biomaterials used in preclinical or clinical studies;
- Validation of drugs and compounds in 3D in vitro systems using human pluripotent stem cell-derived cells;
Organ-on-a-chip and body-on-a-chip platforms.
Dr. Claudia Miranda
Dr. Paola Sanjuan Alberte
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Pluripotent stem cells
- Stem cell engineering
- Bioengineering
- Organoids
- Biomaterials
