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Applied Sciences
Special Issues
Current Advances in Periodontal and Peri-Implant Diseases
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Current Advances in Periodontal and Peri-Implant Diseases

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Dentistry and Oral Sciences".

Deadline for manuscript submissions: closed (20 November 2023) | Viewed by 1031

Special Issue Editors

Dr. Takehito Ouchi

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Guest Editor
Department of Physiology, Tokyo Dental College, 2-9-18, Kanda-Misaki-cho, Chiyoda-ku, Tokyo 101-0061, Japan
Interests: cancer stem cells; homeostasis; genetic regulation
Special Issues, Collections and Topics in MDPI journals
Dr. Shogo Maekawa

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Guest Editor
Department of Periodontology, Tokyo Medical and Dental University 1-5-45, Yushima, Bunkyo-ku, Tokyo 113-8510, Japan
Interests: tissue regeneration; biomaterials; tissue engineering; periodontics; periodontal regeneration; implant dentistry
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Periodontal and peri-implant diseases are crucial concerns in oral health all over the world. They are characterized by multifactorial etiology, including the disruption of the oral microbiota, mechanical stress, and systemic disorders, such as diabetes mellitus. The removal of microbial pathogens is imperative in current periodontal treatment. In addition, a variety of surgeries have been widely performed, such as the application of biomaterials to address periodontal defects and to achieve esthetic periodontal tissue appearance. However, genuine periodontal tissue regeneration has not yet been established. Understanding the onset background, intercellular crosstalk, and genomic regulation is essential to elucidate the process of periodontal regeneration. This Special Issue summarizes the basic and clinical knowledge of periodontal/peri-implant tissue regeneration and highlights the potential of next-generation treatments for periodontal/peri-implant diseases.

Dr. Takehito Ouchi
Dr. Shogo Maekawa
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • periodontal tissue regeneration
  • tissue engineering
  • periodontitis
  • peri-implantitis
  • biomaterials
  • tissue augmentation

Published Papers (1 paper)

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Research

14 pages, 3824 KiB  
Article
Experimental Study for the Evaluation of Titanium Disc Decontamination and Osseointegration in the Rabbit Tibia Model
by Hye Jin Kim, Kyoungseok Choi, Chulyoung Park, Ji Hyun Kim, Jaeyoung Ryu, Seunggon Jung, Min-Suk Kook, Hee-Kyun Oh, Yun Kyong Lim, Joong-Ki Kook and Hong-Ju Park
Appl. Sci. 2023, 13(20), 11177; https://doi.org/10.3390/app132011177 - 11 Oct 2023
Viewed by 788
Abstract
Peri-implantitis is an inflammatory lesion leading to bone destruction resulting from bacterial infection and biofilm formation. Treatments of peri-implantitis aim at bacterial controls and decontamination to promote re-osseointegration. The present study aimed to assess the decontamination of biofilm and the osseointegration of titanium [...] Read more.
Peri-implantitis is an inflammatory lesion leading to bone destruction resulting from bacterial infection and biofilm formation. Treatments of peri-implantitis aim at bacterial controls and decontamination to promote re-osseointegration. The present study aimed to assess the decontamination of biofilm and the osseointegration of titanium discs in a rabbit tibia model. Discs were immersed in culture medium inoculated with Staphylococcus aureus and incubated at 37 °C for 24 h and allocated to different treatments (n = five per group). The decontamination methods were an air-polishing system, 0.12% chlorhexidine rinse, and Er:Yag laser treatments. Each disc from the experimental groups was observed using scanning electron micrography. The rest of the discs were then implanted in four male New Zealand rabbits. Histological and radiographic evaluations were performed. For the quantification of bone density in radiographic data, the fractal dimension (FD) and mean grayscale value (GV) were measured. The Kruskal–Wallis test was used to compare bone density (p < 0.05). Statistically significant differences in FD were observed between the air-polishing treatment with chlorhexidine rinse and the air-polishing treatment with chlorhexidine rinse and Er:Yag laser treatment compared to the contaminated group (p < 0.05). Also, there were statistically significant differences in the results obtained for the group undergoing air-polishing treatment with chlorhexidine rinse and Er:Yag laser treatment compared to the contaminated group (p < 0.05). The decontamination method using air polishing treatment, chlorhexidine rinse, and Er:Yag treatment showed favorable osseointegration with good bone quality. Full article
(This article belongs to the Special Issue Current Advances in Periodontal and Peri-Implant Diseases)
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