Ultrasonic and Photonic Technologies for Biomedical Imaging and Elastography

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Biomedical Engineering".

Deadline for manuscript submissions: 20 June 2024 | Viewed by 3480

Special Issue Editors

School of Science and Engineering, University of Dundee, Dundee DD1 4HN, UK
Interests: elastography; optical coherence tomography; tissue charactersation; surface acoustic wave; bio-optics

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Guest Editor
School of Science and Engineering, University of Dundee, Dundee DD1 4HN, UK
Interests: photoacoustic imaging; optical imaging; ultrasound imaging
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
School of Science and Engineering, University of Dundee, Dundee DD1 4HN, UK
Interests: medical ultrasound and photonics

Special Issue Information

Dear Colleagues,

Light and sound have become essential imaging tool in biomedical engineering. Lasers are routinely used for high-resolution imaging for scientific and medical purpose, and real-time ultrasound imaging has become the dominant clinical imaging modality in the health care system. Light and sound can also be integrated photonic–ultrasonic techniques, including photoacoustics imaging and laser ultrasound systems for medical and non-medical applications. Moreover, elastography technology, as an extention of the function of current optical and ultrasound imaging systems, can be a very useful tool for clinical applications, e.g., cancer localization and diagnosis. Current development of elastography techniques integrate light and sound in a more interesting way, for example, in optical coherence elastography (OCE), focused ultrasound stimulates propagating surface waves in the soft tissues tracked with real-time. The field of biomedical optics and ultrasonics continues to fascinate scientists, engineer, and users by unending production of new ideas and the rapid development of new methods, instruments applications, and the expansion of clinical implementations.

The goal of this Special Issue is to explore recent research findings and technical developments in biomedical optics and ultrasonics, and their elastography function. Many technologies and instrumentations have been successfully translated into biomedical applications ranging from clinical diagnosis to molecular biology. Herein are the many challenges and opportunities for collaborative research and development. Several recent breakthroughs, development trends, and potential uses in conjunction with other techniques are also welcome. Biomedical optics and ultrasonics-based imaging technologies impact a very wide and disparate range of clinical specialties (ophthalmology, endoscopy, dermatology, infectious diseases, surgery, etc.). Potential topics include, but are not limited to, novel methods and instrument designs, in vivo imaging and measurement technology of the human detection and characterization of diseases, and molecular imaging. Topics of particular interest include, but are not limited to, the following topics in:

  • bio-optical imaging
  • ultrasound imaging
  • elastography
  • multimodal imaging
  • machine learning and image processing
  • microscopy
  • tissue optics and spectroscopy
  • focused ultrasound
  • photoacoustic imaging and spectroscopy
  • clinical ultrasound

Dr. Chunhui Li
Dr. James Joseph
Prof. Dr. Zhihong Huang
Guest Editors

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Keywords

  • bio-optical imaging
  • ultrasound imaging
  • elastography
  • multimodal imaging
  • machine learning and image processing
  • microscopy
  • tissue optics and spectroscopy
  • focused ultrasound
  • photoacoustic imaging and spectroscopy
  • clinical ultrasound

Published Papers (2 papers)

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Research

14 pages, 3318 KiB  
Article
Characterization of Flexor Digitorum Superficialis Muscle Stiffness Using Ultrasound Shear Wave Elastography and MyotonPRO: A Cross-Sectional Study Investigating the Correlation between Different Approaches
by Phongpan Tantipoon, Nuttaporn Praditpod, Markus Pakleppa, Chunhui Li and Zhihong Huang
Appl. Sci. 2023, 13(11), 6384; https://doi.org/10.3390/app13116384 - 23 May 2023
Cited by 1 | Viewed by 1386
Abstract
Muscle stiffness provides a key insight toward clinical assessment for rehabilitation. Regarding the high-cost and technical skill requirement of ultrasound shear wave elastography (SWE) restricting extensive clinical use, MyotonPRO has been proposed as a complementary tool for muscle stiffness measurement. There is a [...] Read more.
Muscle stiffness provides a key insight toward clinical assessment for rehabilitation. Regarding the high-cost and technical skill requirement of ultrasound shear wave elastography (SWE) restricting extensive clinical use, MyotonPRO has been proposed as a complementary tool for muscle stiffness measurement. There is a deficiency of studies revealing the use of this tool for measuring muscle stiffness contributing to hand control. The purpose of this study was to assess the capability and effectiveness of MyotonPRO and SWE for hand muscle stiffness characterization. The stiffness of the dominant flexor digitorum superficialis (FDS) muscle of 25 healthy participants (12 males and 13 females) aged 29.60 ± 9.81 years was evaluated while they performed grip tasks. The muscle stiffness of males and females was compared. The correlation between dynamic muscle stiffness given by MyotonPRO and Young’s modulus obtained from SWE was investigated. Statistical analysis indicated a significant difference in the dynamic muscle stiffness between genders in all conditions (p < 0.05), whereas a significant difference in Young’s modulus was found only at the resting state. A moderate correlation was found between dynamic muscle stiffness and Young’s modulus (r ranged from 0.243 to 0.489). Therefore, MyotonPRO can be used to assess the muscle stiffness of the FDS muscle at rest and during muscle contraction. Full article
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20 pages, 5240 KiB  
Article
A Novel Approach to Tele-Ultrasound Imaging: Compressive Beamforming in Fourier Domain for Ultrafast Ultrasound Imaging
by Xinyu Zhang, Yiwen Xu, Ninghao Wang, Yang Jiao and Yaoyao Cui
Appl. Sci. 2023, 13(5), 3127; https://doi.org/10.3390/app13053127 - 28 Feb 2023
Cited by 1 | Viewed by 1513
Abstract
Tele-ultrasound imaging is useful in various situations. Plane wave imaging provides a method for ultrafast ultrasound with very high frame rates, which sacrifices image quality and leads to the problem of a large amount of data and low signal transmission speed in telemedicine [...] Read more.
Tele-ultrasound imaging is useful in various situations. Plane wave imaging provides a method for ultrafast ultrasound with very high frame rates, which sacrifices image quality and leads to the problem of a large amount of data and low signal transmission speed in telemedicine imaging. In this paper, a novel compressive frequency-wavenumber domain beamforming method is introduced, which integrates Stolt’s f-k method and compressed sensing theory on the lateral wavenumber. The data load is reduced by the sparsity of the echo signal parallel to the transducer, which requires a smaller measurement matrix during compressed sensing to reduce memory usage and accelerate the transmission rate. The signal is compressed in the Fourier domain to obtain greater stability and better image quality after reconstruction than if it was compressed in the temporal domain. Simulated data and experimental acquisitions were used to compare compressive Fourier domain beamforming with conventional delay-and-sum (DAS) beamforming. The results showed that compressive beamforming within the wavenumber domain provides the image with higher quality from less data. Full article
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