Oxidative Stress in Cataracts: Mechanisms and Therapies
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 31 August 2024 | Viewed by 153
Special Issue Editors
Interests: mechanism of cataract formation; lens protein thiolation; oxidative damage; glutathione; glutaredoxin and thioredoxin enzyme systems; redox signaling; redox regulation
Interests: eyes; ocular diseases; cataracts
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cataracts, a widespread and leading cause of vision impairment worldwide, manifest as clouding of the eye's natural lens. This clouding effect can progressively obstruct vision, leading to difficulties in daily activities and a reduced quality of life for affected individuals.
One of the key mechanisms underlying the formation of cataracts is oxidative stress. Oxidative stress occurs when there is an imbalance between the production of harmful reactive oxygen species (ROS) and the body's ability to neutralize them with antioxidants. In the eye, this imbalance can lead to the oxidation of proteins and lipids within the lens, causing structural changes that result in cloudiness and opacity.
This Special Issue aims to gather cutting-edge research from experts in the field, highlighting the pivotal role of oxidative stress in cataract pathogenesis. It will cover topics such as:
- The role of oxidative stress in cataract initiation and maturation;
- The molecular pathways and signaling involved in oxidative-stress-induced lens damage;
- The effects of dietary and environmental factors on oxidative stress and cataracts;
- The potential of natural and synthetic antioxidants as therapeutic agents for cataracts;
- The challenges and opportunities for developing novel antioxidant-based strategies for cataract prevention and treatment.
Prof. Dr. Marjorie F. Lou
Dr. Hongli Wu
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cataract
- Posterior Capsule Opacification (PCO)
- oxidative damage
- antioxidant
- redox regulation
