Redox Regulation during Mucosal Host-Microbe Interactions
A special issue of Antioxidants (ISSN 2076-3921).
Deadline for manuscript submissions: closed (15 January 2022) | Viewed by 3980
Special Issue Editors
2. Department of Medical Microbiology, Maastricht University, Maastricht, The Netherlands
Interests: extracellular vesicles; inhalation toxicology; thiol biology; respiratory disease; infectious disease
Interests: extracellular vesicles, acute and chronic inflammatory diseases, redox biology, (dietary) antioxidants
Special Issue Information
Dear Colleagues,
The redox status exerts important regulatory functions during host-microbe interactions at mucosal surfaces. Chronic mucosal inflammation (e.g. in inflammatory bowel disease or chronic obstructive pulmonary disease) is associated with a pro-oxidant state, as well as microbiome dysbiosis. Furthermore, bacterial, viral and other infections dysregulate the host redox balance by interfering with cellular metabolism. Finally, host cells and pathogens actively influence the redox status during infection as a combat strategy. Host phagocytes produce reactive oxygen species (ROS) to fight infections, while numerous pathogens use ROS as virulence factors or employ antioxidant strategies to defend themselves against oxidative attacks by the host or other, competing microbes. The administration of antioxidants may have therapeutic potential by preventing tissue damage, promoting pathogen clearance or restoring microbiome composition. In this Special Issue, we aim to compile the most recent data from fundamental and clinical research on the role of an altered redox balance during mucosal host-microbe interactions in homeostasis, chronic inflammation and infection. This special issue welcomes full length manuscripts and short communications, including original research, review articles and concept papers.
We are looking forward to your contributions.
Dr. Birke J. Benedikter
Dr. Antje R. Weseler
Dr. Carla Bellinghausen
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
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Keywords
- oxidative stress
- redox balance
- microorganisms
- infection
- mucosa
- immunity
- antioxidants
- oxidative burst
- phagocytosis
