Special Issue "Natural Antioxidants: Multiple Mechanisms for Skin Protection"
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 1 December 2023 | Viewed by 13320
Interests: bioactive natural products; nutraceuticals and cosmeceuticals; ferroptosis; senescence
Special Issues, Collections and Topics in MDPI journals
Human skin is the largest organ, covering the body and protecting us against environmental insults. Although it is a robust defensive system, the skin can be susceptible to both internal stress (e.g., oxidation, glycation, and inflammation) and external stimuli, including mechanical damage, ultraviolet (UV) radiation, toxic chemicals, and the invasion of microorganisms. These factors can collectively undermine the structural integrity and biological functions of the skin, which leads to skin aging and other undesired conditions. To ameliorate these insults to the skin, natural antioxidants (e.g., phytochemicals from medicinal plants and functional foods, as well as their synthetic derivatives) have been used as treatments for dermatological maladies and/or active ingredients for cosmetic products. The skin protective effects of natural antioxidants are supported by numerous published preclinical studies (with in vitro and in vivo experimental models). However, only a paucity of human clinical trials has reported the efficacy of natural products’ skin protection. This is, at least partially, attributed to the lack of understanding of natural antioxidants’ mechanisms of action (MOA) at the molecular level. In recent decades, mechanistic studies on the skin protection of natural antioxidants have been greatly promoted by various advanced biophysical and biochemical technologies, which enabled researchers in this field to address research challenges with novel approaches. For instance, sophisticated methods, such as ‘multi-omics’, including genomics, epigenomics, proteomics, lipidomics, metabolomics, and microbiomics, are adopted to provide an integrated perspective to power investigation across multiple levels of biology.
Herein, this Special Issue (SI), entitled Natural Antioxidants: Multiple Mechanisms for Skin Protection, aims to provide a platform for researchers to showcase their studies in fields related to skin protection by natural antioxidants. This SI includes (but is not limited to) the following research topics: (1) evaluations of natural antioxidants’ skin protective effects; (2) the investigation of mechanisms of action; (3) the development of natural antioxidants and their derivatives as new cosmeceutical ingredients; (4) the applications of ‘multi-omics’ approaches; and (5) the discovery of the molecular target(s) of action. Studies in this SI can be published in the format of a research article, review, perspective, and short communication.
Prof. Dr. Hang Ma
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- natural products
- mechanism(s) of action
- multi-omics approaches
- target identification
- dermatological treatment
- skin protection
- skin cancers
- skin aging