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Antioxidants
Special Issues
The Role of Aerobic Exercise in the Cardiovascular Antioxidant System
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The Role of Aerobic Exercise in the Cardiovascular Antioxidant System

A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".

Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 1854

Special Issue Editors

Dr. Edilamar Menezes De Oliveira

E-Mail Website
Guest Editor
Laboratory of Biochemistry and Molecular Biology of Exercise, School of Physical Education and Sport, University of Sao Paulo, Sao Paulo 05508-030, Brazil
Interests: investigates the effects of physical training on non-coding RNAs in the cardiovascular system; focusing on heart and skeletal muscle microRNAs; effects of physical training on myocardial infarction, hypertension, diabetes and breast and colon cancer
Dr. Leonardo Yuji Tanaka

E-Mail Website
Guest Editor
Vascular Biology Laboratory, LIM-64 (Translational Cardiovascular Biology), Instituto do Coração (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo 05508-030, Brazil
Interests: exercise; vascular biology; redox signaling and cytoskeleton

Special Issue Information

Dear Colleagues,

The significant effect of aerobic exercise on cardiovascular health is widely recognized. However, the mechanisms triggered by acute exercise sessions or an aerobic training, which promote cellular- or systemic-stress-responsive signaling to support chronic adaptations, are far from being understood. In particular, the role of the antioxidant system in redox signal compartmentalization and the converging endpoint for downstream adaptation on cardiovascular system is of great importance and will be highlighted through original and review contributions in this Special Issue. Other topics of interest include mediators and post-transcriptional and post-translational modifications and their impact on acute and chronic cardiovascular adaptation to the antioxidant response; the comparison of health and pathological conditions; the interaction of physical exercise with antioxidants or additional interventions for the cardiovascular system; aerobic exercise training to investigate the effect of targeting different molecular, cellular, and systemic aspects on cardiovascular antioxidant response. We look forward to receiving your contributions.

Dr. Edilamar Menezes De Oliveira
Dr. Leonardo Yuji Tanaka
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • physical exercise
  • cardiovascular system
  • redox signaling
  • antioxidants
  • exercise training
  • non-coding RNAs
  • myocardium infarct
  • hypertension
  • skeletal muscle

Published Papers (1 paper)

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Research

22 pages, 1623 KiB  
Article
Differential Effects of Very-Low-Volume Exercise Modalities on Telomere Length, Inflammation, and Cardiometabolic Health in Obese Metabolic Syndrome Patients: A Subanalysis from Two Randomized Controlled Trials
by Dejan Reljic, Adriana Koller, Hans J. Herrmann, Arif B. Ekici, Markus F. Neurath and Yurdagül Zopf
Antioxidants 2023, 12(10), 1847; https://doi.org/10.3390/antiox12101847 - 11 Oct 2023
Viewed by 1509
Abstract
Oxidative stress (OS) and inflammation are features of metabolic syndrome (MetS) that can contribute to the shortening of telomere length (TL), a marker of cellular ageing. Research indicates that exercise can positively influence MetS-associated conditions and TL. However, the effects of low-volume exercise [...] Read more.
Oxidative stress (OS) and inflammation are features of metabolic syndrome (MetS) that can contribute to the shortening of telomere length (TL), a marker of cellular ageing. Research indicates that exercise can positively influence MetS-associated conditions and TL. However, the effects of low-volume exercise types on TL are still unknown. We investigated the impact of very-low-volume high-intensity interval training (LV-HIIT), one-set resistance training (1-RT), and whole-body electromyostimulation (WB-EMS) on TL, inflammation, and cardiometabolic indices in 167 MetS patients. Data were derived from two randomized controlled trials where patients were allocated to an exercise group (2 sessions/week, for 12 weeks) or a control group. All groups received standard-care nutritional weight loss counselling. TL was determined as the T/S ratio (telomere to single-copy gene amount). All groups significantly reduced body weight (p < 0.05), but the T/S-ratio (p < 0.001) only increased with LV-HIIT. OS-related inflammatory markers (C-reactive protein, interleukin-6, and lipopolysaccharide-binding protein) only decreased (p < 0.05) following LV-HIIT. The MetS severity z-score improved with LV-HIIT (p < 0.001) and 1-RT (p = 0.014) but not with WB-EMS. In conclusion, very-low-volume exercise modalities have differential effects on telomeres, inflammation, and cardiometabolic health. Only LV-HIIT but not strength-based low-volume exercise increased TL in MetS patients, presumably due to superior effects on OS-related inflammatory markers. Full article
(This article belongs to the Special Issue The Role of Aerobic Exercise in the Cardiovascular Antioxidant System)
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