Oxidative Stress in Red Blood Cells

A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".

Deadline for manuscript submissions: closed (20 April 2024) | Viewed by 294

Special Issue Editors


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Guest Editor
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno D’Alcontres 31, 98166 Messina, Italy
Interests: oxidative stress events; glycation; aging; membrane transport systems
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, 98166 Messina, Italy
Interests: oxidative stress events; glycation; aging; membrane transport systems
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Red blood cells (RBCs) are unique and highly specialized cells. Being involved in respiratory gas transportation and highly susceptible to oxidative damage, they are equipped with effective anti-oxidative systems providing them with antioxidant protection, along with protection for body tissues and organs. When oxidants are produced in excess or when the antioxidant defences are ineffective, the resulting oxidative condition, which in some cases is useful for cell growth and signaling, causes both biochemical and biophysical deleterious effects, e.g., disruption in the bilayer molecular arrangement, changes in morphology and mechanics, thus compromising RBC homeostasis, which may correlate with the development of oxidative-stress-related diseases.

This Special Issue will focus on the molecular mechanisms underlying the cell redox endogenous system and oxidative stress (OS) in RBCs, with specific regard to the OS impact on cellular components, including membrane ion transport systems. The aim is also to provide more information about cell response to OS in human pathologic conditions, mainly in those displaying systemic OS as a hallmark, and its possible modulation by novel antioxidant strategies. In this regard, molecular targets at the level of the cellular membrane and their potential modulation under OS will be also considered. The beneficial effects of antioxidants and possible cell adaptation mechanisms to OS will be worthy of note. Studies using animal or cell models, as well as clinical studies are welcome.

The Special Issue welcomes high-quality research articles and review articles focusing on the relationship between OS and RBC responses.

Dr. Angela Marino
Dr. Rossana Morabito
Dr. Alessia Remigante
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • erythropoiesis
  • membrane transports
  • biophysical and biochemical RBC properties
  • blood bank storage
  • adaptations to stress
  • the use of RBCs as drug carriers or biomarkers

Published Papers

There is no accepted submissions to this special issue at this moment.
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