Dear Colleagues,

Commercial animal/poultry production is associated with a range of stresses, including environmental, technological, nutritional and internal stresses. In fact, it is practically impossible to prevent stresses and development of strategies to stress protection has become a hot topic in recent years. It was proven that at molecular level most stresses are associated with overproduction of free radicals, oxidative stress and redox imbalance. Furthermore, free radical bad image has been recently changed and redox signaling became an important topic of current research. It seems likely that stress adaptation is related to activation of various transcription factors, including Nrf2 and NF-κB, and vitagenes. In general, maintenance of the optimal redox status is key task for the integrated antioxidant defence network. In stress conditions of commercial animal/poultry production the antioxidant defence system needs external help provided by dietary supplementation of traditional antioxidants such as vitamin E, or other nutrients possesing regulatory functions in the antioxidant defences, including taurine, carnitine, and some others. The important task for a nutritionist is to find an optimal balance of dietary antioxidants to provide animals with maximum antioxidant defences, effective stress signaling and adaptation which would be vital elements in gut health maintenance, immunocompetence, controlling inflammation and maintenance of high productive and reproductive performance of animals/poultry.

This special issue would be devoted to redox homeostasis maintenance in poultry/animal production to provide optimal health and high stress resistance under commercially relevant stress conditions.

This would include, but not restricted to, such topics as:

• Molecular mechanisms of redox balance regulation
• Redox homeostasis and immunity
• Oxidative stress, antioxidant defences and inflammation
• Commercial stresses, redox balance and gut health
• Redox balance, microbiota and animal/poultry health
• Dietary selenium, selenoproteins and stress adaptation in farm animals and poultry
• Vitamin E, as a headquarter of the antioxidant defence network
• Carotenoids: is there biological requirement for them in poultry and farm animals?
• Carnitine and taurine: new entrants into the antioxidant family and their roles in redox homeostasis maintenance
• Redox homeostasis and meat quality
• Redox balance, antioxidant defences and male reproduction
• Redox homeostasis during chicken embryonic development and mammal’s pregnancy and its regulation
• Nrf2 in poultry and animal production: a conductor of the antioxidant defence orchestra
• NF-kB as a marker and regulatory hub in redox balance maintenance in farm animals and poultry
• Vitagenes in redox balance maintenance.

Prof. Dr. Peter F. Surai
Guest Editor

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• redox homeostasis
• oxidative stress
• antioxidants
• transcription factors
• immunity
• inflammation
• poultry
• pigs
• cattle