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Antibiotics
Special Issues
Healthcare-Associated Infections (HAIs): Prevention, Control, and Antibiotic Stewardship
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Healthcare-Associated Infections (HAIs): Prevention, Control, and Antibiotic Stewardship

A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Antibiotics Use and Antimicrobial Stewardship".

Deadline for manuscript submissions: closed (31 March 2024) | Viewed by 2762

Special Issue Editor

Dr. Hosoon Choi

E-Mail Website
Guest Editor
Central Texas Veterans Research Foundation, Temple, PA, USA
Interests: SARS-CoV-2 sequencing; antigenicity of SARS-CoV-2 and immune response. bacterial whole genome sequencing; antimicrobial resistance research

Special Issue Information

Dear Colleagues,

Healthcare-Associated Infections (HAIs), also known as nosocomial infections, are a significant concern within the healthcare industry worldwide. HAIs can lead to severe complications, prolonged hospital stays, increased healthcare costs, and even mortality.

The prevention, control, and antibiotic stewardship of HAIs are essential in safeguarding patient health and the integrity of healthcare systems. By implementing strict infection control measures, responsible antibiotic use, and sterile procedural techniques, healthcare facilities can significantly reduce the incidence of HAIs, improve patient outcomes, and contribute to the global fight against antibiotic resistance. Addressing HAIs remains a top priority in healthcare, as it is essential for providing safe and effective medical care to all patients.

This Special Issue seeks manuscript submissions that further our knowledge of the prevention and treatment of healthcare-associated infections and antibiotic stewardship in all healthcare settings.

Dr. Hosoon Choi
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • healthcare-associated infections
  • antibiotic stewardship
  • antibiotics
  • prevention
  • control

Published Papers (2 papers)

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Research

16 pages, 1080 KiB  
Article
Estimation of Additional Costs in Patients with Ventilator-Associated Pneumonia
by Ginger G. Cabrera-Tejada, Pablo Chico-Sánchez, Paula Gras-Valentí, Francisco A. Jaime-Sánchez, Maria Galiana-Ivars, Sonia Balboa-Esteve, Isel L. Gómez-Sotero, José Sánchez-Payá and Elena Ronda-Pérez
Antibiotics 2024, 13(1), 2; https://doi.org/10.3390/antibiotics13010002 - 19 Dec 2023
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Abstract
Healthcare-associated infections (HAIs) present a global public health challenge, contributing to high morbidity and mortality and substantial economic burdens. Ventilator-associated pneumonia (VAP) ranks as the second most prevalent HAI in intensive care units (ICUs), emphasizing the need for economic analyses in this context. [...] Read more.
Healthcare-associated infections (HAIs) present a global public health challenge, contributing to high morbidity and mortality and substantial economic burdens. Ventilator-associated pneumonia (VAP) ranks as the second most prevalent HAI in intensive care units (ICUs), emphasizing the need for economic analyses in this context. This retrospective cohort study, conducted at the General Hospital of Alicante from 2012 to 2019, aimed to assess additional costs related to VAP by comparing the extended length of stay for infected and non-infected ICU patients undergoing mechanical ventilation (MV) for more than 48 h. Employing propensity score association, 434 VAP patients were compared to an equal number without VAP. The findings indicate a significantly longer mechanical ventilation period for VAP patients (17.40 vs. 8.93 days, p < 0.001), resulting in an extra 13.56 days of stay and an additional cost of EUR 20,965.28 per VAP episode. The study estimated a total cost of EUR 12,348,965.28 for VAP during the study period, underscoring the economic impact of VAP. These findings underscore the urgent need for rigorous infection surveillance, prevention, and control measures to enhance healthcare quality and reduce overall expenditures. Full article
(This article belongs to the Special Issue Healthcare-Associated Infections (HAIs): Prevention, Control, and Antibiotic Stewardship)
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12 pages, 2246 KiB  
Article
Evaluating Healthcare-Associated Infections in Public Hospitals: A Cross-Sectional Study
by Daniela Iancu, Iuliu Moldovan, Brîndușa Țilea and Septimiu Voidăzan
Antibiotics 2023, 12(12), 1693; https://doi.org/10.3390/antibiotics12121693 - 02 Dec 2023
Viewed by 1403
Abstract
Background: Hospital-acquired infections (HAIs) pose a significant danger to global public health, mainly because their numbers are growing exponentially each year. Additionally, the rise of bacterial strains resistant to current treatment options further exacerbates this threat. This study aimed to examine the occurrences [...] Read more.
Background: Hospital-acquired infections (HAIs) pose a significant danger to global public health, mainly because their numbers are growing exponentially each year. Additionally, the rise of bacterial strains resistant to current treatment options further exacerbates this threat. This study aimed to examine the occurrences of HAIs identified in public hospitals at the county level. Methods: We conducted a cross-sectional study utilizing data provided to the Mures Public Health Directorate from all the public hospitals within the studied county. We examined HAIs reported during the period spanning from 2017 to 2021, which amounted to a total of 4603 cases. Results: The medical departments reported the highest prevalence of HAIs at 48.25%. The most common infections included enterocolitis with Clostridioides difficile (32.61%), COVID-19 (19.83%), bronchopneumonia (16.90%), sepsis, surgical wound infections, and urinary tract infections. The five most frequently identified pathogens were Clostridioides difficile (32.61%), SARS-CoV-2 (19.83%), Acinetobacter baumannii (11.82%), Klebsiella pneumoniae (9.58%), and Pseudomonas aeruginosa (7.95%). Acinetobacter baumannii was the predominant agent causing bronchopneumonia, while Klebsiella pneumoniae was the leading cause of sepsis cases. Escherichia coli was the primary agent behind the urinary tract infections, and Staphylococcus aureus MRSA was identified as the main etiology for wound infections and central catheter infections. Throughout the study period, there was a significant rise in Clostridioides difficile and Gram-negative bacteria prevalence rates. Conclusions: This study identified increased Clostridioides difficile in HAI cases during COVID-19, highlighting the need for careful antibiotic use and emphasizing the growing challenge of multi-resistant strains in post-pandemic state hospitals. Full article
(This article belongs to the Special Issue Healthcare-Associated Infections (HAIs): Prevention, Control, and Antibiotic Stewardship)
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