Antimicrobial Stewardship and Optimizing Antibiotic Dose in Critically Ill Patients
A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Antibiotics Use and Antimicrobial Stewardship".
Deadline for manuscript submissions: 30 September 2024 | Viewed by 695
Special Issue Editor
Special Issue Information
Dear Colleagues,
The escalating crisis of antibiotic resistance, coupled with a decrease in the development of novel antibiotics, demands innovative approaches to improve current antimicrobial prescribing practices. This Special Issue focuses on antimicrobial stewardship and optimizing antibiotic dose in critically ill patients, highlighting the challenges clinicians face in striking the balance between effective therapy and minimizing antibiotic resistance.
In clinical practice, ensuring appropriate antibiotic dosing is essential for therapeutic success in critically ill patients. Critical illness has profound effects on the pharmacokinetics and pharmacodynamics of antibiotics. Patients are at an increased risk of both under- and overdosing of drugs, leading to either therapeutic failure, antibiotic resistance or toxicity. We suggest that the articles submitted to this Special Issue focus on the importance of individualizing antibiotic therapy, developing dynamic prescribing practices, incorporating clinical susceptibility data and employing pharmacokinetic/pharmacodynamic principles for dose optimization.
Additionally, this issue will cover the antimicrobial stewardship programs (ASPs) that promote responsible antibiotic use. By integrating these programs into the healthcare system, healthcare professionals can align their prescribing practices with evidence-based guidelines and minimize the development of resistant strains. The need for collaboration between different disciplines—such as infection control, microbiology, clinical pharmacy and therapeutics—is underscored throughout this issue to maximize the outcomes of ASPs.
Prof. Dr. Barbara J. Philips
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- antibiotics
- antimicrobials
- intensive care
- critical care
- sepsis
- pharmacokinetics
- pharmacodynamics
- stewardship
- beta-lactams
- aminoglycosides
- quinolones
- cephalosporins
- antifungal
