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Veterinary Sciences
Special Issues
Respiratory Diseases of Small Animals
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Respiratory Diseases of Small Animals

A special issue of Veterinary Sciences (ISSN 2306-7381). This special issue belongs to the section "Veterinary Internal Medicine".

Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 10916

Special Issue Editors

Prof. Dr. Jesus Talavera Lopez

E-Mail Website
Guest Editor
1. Department of Animal Medicine and Surgery, University of Murcia, 30100 Murcia, Spain
2. Cardiorespiratory Service, Veterinary Teaching Hospital, University of Murcia, 30100 Murcia, Spain
Interests: biomarkers; endoscopic techniques; fluoroscopy/dynamic evaluation of airways diseases; regenerative medicine; lung ultrasonography; pulmonary function tests
Dr. Iván Miralles-Plaza

E-Mail Website
Guest Editor
Cardiorespiratory Service, Veterinary Teaching Hospital, University of Murcia, 30100 Murcia, Spain
Interests: mechanical ventilation; blood gas analysis; intensive care; respiratory endoscopy; parasitology, infectious diseases; interstitial diseases; pulmonary hypertension

Special Issue Information

Dear Colleagues,

Clinical signs of respiratory tract disease, such as coughing, sneezing, and exercise intolerance, are frequently listed as clinical problems during the diagnostic processes involving small animals. In the emergency medicine context, animals that present in respiratory distress pose difficult and sometimes stressful management challenges because of their inherent fragility. The clinical manifestations of respiratory diseases cover a wide range of severity, from intermittent to other, more persistent presentations that greatly reduce the quality of life of the affected animals and their environment (i.e., chronic cough) to clinical symptoms that evolve slowly or rapidly and can seriously compromise life. Each individual case requires a tailored diagnostic approach supported by good clinical protocols and the availability of advanced diagnostic tools. The high presentation rate of these disorders drives the continuous interest and research efforts by the veterinary medical–scientific community, which allows respiratory diseases to be better defined and detected earlier, as well as the for treatment protocols that are better adapted to each particular patient to be established, promoting the appearance of new treatments.

Research areas may include all aspects of veterinary pneumology (but are not limited to) the following: physiology, pathophysiology, epidemiology, and diagnostic testing or treatment of the canine and feline species, including preclinical and clinical research.

This Special Issue of Veterinary Sciences, titled Respiratory Diseases of Small Animals, will publish original articles, review, communications, case reports on the latest studies in respiratory diseases in small animals.

Prof. Dr. Jesus Talavera Lopez
Dr. Iván Miralles-Plaza
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Veterinary Sciences is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nasal-paranasal
  • nasopharynx
  • larynx
  • trachea
  • bronchus
  • collapse
  • pleura
  • mediastinum
  • pulmonary parenchyma
  • intersticium
  • pulmonary vascularization
  • lung
  • parasites
  • asthma
  • stenting
  • pulmonary function tests
  • distress
  • cough
  • sneezing
  • reverse sneezing
  • stridor
  • stertor
  • cyanosis
  • nebulization
  • aerosol
  • stem cells

Published Papers (3 papers)

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Research

10 pages, 2213 KiB  
Article
Intranasal and Serum Gentamicin Concentration: Comparison of Three Topical Administration Protocols in Dogs
by Tom Biénès, Aurélie Lyssens, Hélène Machiels, Marie Eve Hercot, Aline Fastres, Tutunaru Alexandru-Cosmin, Marine Deville, Corinne Charlier, Frédéric Billen and Cécile Clercx
Vet. Sci. 2023, 10(8), 490; https://doi.org/10.3390/vetsci10080490 - 28 Jul 2023
Cited by 1 | Viewed by 1389
Abstract
Antimicrobials’ topical administration efficacy has not been assessed in dogs with upper respiratory tract disease. The aim was to compare the concentration of gentamicin in nasal lavage fluid (NALF) and in serum after three topical protocols. This was a prospective crossover study of [...] Read more.
Antimicrobials’ topical administration efficacy has not been assessed in dogs with upper respiratory tract disease. The aim was to compare the concentration of gentamicin in nasal lavage fluid (NALF) and in serum after three topical protocols. This was a prospective crossover study of ten healthy dogs. Gentamicin was nebulized for a duration of 1 week, twice a day, for 10 min in the first protocol (10-min protocol) and for 3 min in the second protocol (3-min protocol), while the third protocol consisted of the administration of 0.25 mL of gentamicin in each nostril (drop protocol). Median concentrations of gentamicin in NALF were 9.39 µg/mL (8.12–19.97 interquartile range), 4.96 µg/mL (4.60–6.43) and 137.00 µg/mL (110.5–162.00) in the 10-min protocol, 3-min protocol and drop protocol, respectively. The result for the drop protocol was significantly higher than those of both nebulization protocols in NALF (p = 0.039). In serum, the gentamicin concentration was 0.98 µg/mL (0.65–1.53) and 0.25 µg/mL (0.25–0.44) in the 10-min and 3-min protocols, respectively. Gentamicin was not detected in the serum of seven out of ten dogs in the drop protocol, and gentamicin was significantly higher in the 10-min protocol compared to the drop protocol (p = 0.001). This study found that the 10-min, 3-min and drop protocols achieved superior concentrations in NALF compared to the minimum inhibitory concentration for gentamicin-sensitive bacteria, while remaining below the toxic values in blood. Full article
(This article belongs to the Special Issue Respiratory Diseases of Small Animals)
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13 pages, 6529 KiB  
Article
Epidemiological Investigation of Feline Upper Respiratory Tract Infection Encourages a Geographically Specific FCV Vaccine
by Jindong Gao, Yan Li, Qiyun Xie, Mayasar I. Al-zaban, Fatimah A. Al-Saeed, Ali A. Shati, Amin A. Al-Doaiss, Ahmed Ezzat Ahmed, Shah Nawaz, Hala Ebrahem, Irfan Irshad, Muhammad Fakhar-e-Alam Kulyar and Jiakui Li
Vet. Sci. 2023, 10(1), 46; https://doi.org/10.3390/vetsci10010046 - 9 Jan 2023
Cited by 4 | Viewed by 3263
Abstract
A total of 1158 cats with feline upper respiratory tract infection were incorporated from twenty animal hospitals in Wuhan, China, from April 2019 to April 2022 to investigate the epidemiology of feline calicivirus (FCV), herpesvirus-1 (FHV-1), Mycoplasma felis (M. felis) and [...] Read more.
A total of 1158 cats with feline upper respiratory tract infection were incorporated from twenty animal hospitals in Wuhan, China, from April 2019 to April 2022 to investigate the epidemiology of feline calicivirus (FCV), herpesvirus-1 (FHV-1), Mycoplasma felis (M. felis) and Chlamydia felis (C. felis) for the development of a geographically-specific FCV vaccine with reference to prevalence and risk factors for infection. The 871 samples (75.2%) of kittens were younger than 12 months, of which 693 were males, and 456 were females. Among the samples, 443 were British shorthair cats, accounting for 38.3%, and 252 were Chinese rural cats, accounting for 21.8%. PCR/RT-PCR detection of the above four viruses (FCV, FHV-1, M. felis, and C. felis) in the upper respiratory tract of cats showed that the total positive samples were 744 (64.3%), including 465 positive samples of feline calicivirus, accounting for 40.2% of the total 1158 samples. There were 311 positive samples of M. felis, accounting for 26.9% of the total samples, ranked second in clinical practice. The 180 positive samples of feline herpesvirus accounted for 15.5%, and 85 positive samples of Chlamydia felis accounted for 7.3%. Among them, the number of positive samples of single pathogenic infections was 493, accounting for 66.3% of the total 744 positive samples. Double, triple, and quadruple infections accounted for 28.2%, 5.0%, and 0.5%, respectively, with the highest proportion of single infections. The molecular biological characteristics of the 17 isolated FCVd strains in Wuhan were further analyzed. It was found that the F9 vaccine strain and the antigenic epitopes in the 5’HVR of the E region were collated with the F9 vaccine strain. Moreover, phylogenetic tree analysis showed that the strains related to the F9 and 255 vaccines were distantly related, leading to the failure of the vaccine. In addition, the strains associated with the F9 and 255 vaccines were distant, which might lead to vaccine failure in anticipation of the development of a more phylogenetically close FCV vaccine in China and may require the development of a vaccine for a locally related FCV strain. Full article
(This article belongs to the Special Issue Respiratory Diseases of Small Animals)
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11 pages, 1970 KiB  
Article
Reverse Sneezing in Dogs: Observational Study in 30 Cases
by Jesús Talavera, Patricia Sebastián, Giorgia Santarelli, Ignacio Barrales and María Josefa Fernández del Palacio
Vet. Sci. 2022, 9(12), 665; https://doi.org/10.3390/vetsci9120665 - 29 Nov 2022
Cited by 1 | Viewed by 5098
Abstract
Reverse sneezing (RS) is a frequent reason for veterinary consultation, but there is scarce clinical information. The aim of this study was to describe clinical characteristics in a cohort of 30 dogs with RS. Signalment, clinical features, results of diagnostic tests, final diagnosis, [...] Read more.
Reverse sneezing (RS) is a frequent reason for veterinary consultation, but there is scarce clinical information. The aim of this study was to describe clinical characteristics in a cohort of 30 dogs with RS. Signalment, clinical features, results of diagnostic tests, final diagnosis, and evolution were retrospectively evaluated. Sex and neuter status were equally distributed into diagnosis categories. A significantly higher representation of toys (<5 kg, 50%) and small-sized dogs (5–15 kg, 27%), in comparison to medium (15–30 kg, 17%) and large-sized dogs (>30 kg, 7%), was found. RS was the main owner concern in many of the cases (67%). Many cases presented chronic RS (60%, > 3 months), with more than one episode a week (60%). Most cases had an additional clinical respiratory sign (63%) and an unremarkable physical examination (63%). Inflammatory airway disorders were present in 57% of the cases, followed by anatomical–functional disorders (27%), and nasal/nasopharyngeal foreign bodies (10%). Two dogs (7%) remained as open diagnoses. Episodes of RS were persistent despite the treatment in 61% of the dogs with follow-up. Although some dogs manifest infrequent episodes of RS, being otherwise normal, RS should be considered a marker of potential irritation of the nasopharyngeal mucosa and should always be sufficiently investigated. Full article
(This article belongs to the Special Issue Respiratory Diseases of Small Animals)
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