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Nanomaterials for Chemical Sensors

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Chemical Sensors".

Deadline for manuscript submissions: closed (31 January 2021) | Viewed by 14447

Special Issue Editor


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Guest Editor
Chemical Sensors and Optical Molecular Spectroscopy, Institute of Analytical Chemistry, University of Vienna, 1090 Vienna, Austria
Interests: physicochemical basis of sensors; chemical sensors; physical sensors; metrology; supramolecular chemistry; molecular recognition; molecular imprinting; anisotropic phases
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The needle eye in developing sensors is the design of innovative materials. Thus, this Special Issue is focused on the detection process by coatings. The most innovative trends in this field were initiated by nanotechnology in the last few decades. This strategy meets the challenges of modern chemical sensors: miniaturization, fast responses, reversibility, low energy consumption, and low cost. All these sensor materials have to be combined with suitable transducers such as mass sensitive devices, resistive, capacitive, electrochemical, and optical detection methods. Measurements are possible both in the gaseous and liquid phase.      

In principle, nearly all modern chemical sensors are designed in nano dimensions. This is especially true for the height of chemical coating. Preferably, the materials are organized in nanoparticles. In this case, diffusion occurs in three dimensions, which leads to fast response times. These particles may consist of both organic and inorganic materials. The sensor effects are improved by adapting the polarity of the adsorption/absorption material to the analyte. Furthermore, selectivity is achieved by molecular recognition via supramolecular chemistry. This can be realized, e.g., by molecular imprinting, which leads to highly robust materials. Complex analytes in solution can also be recognized by biomolecules such as aptamers.

Thus, selectivity and high sensitivity can be achieved by molecular interactions in a nanosystem, which leads to fast responses and reversibility.

Prof. Dr. Franz L. Dickert
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Chemical sensors 
  • Coatings
  • Nano particles 
  • Chemical and biochemical recognition
  • Supramolecular chemistry 
  • Polymers
  • Molecular imprinting 
  • Transducers 
  • Electrochemical detection 
  • Mass sensitive devices
  • Optical procedures 
  • Gases, VOCs 
  • Lean molecules 
  • PAHs and PCBs 
  • Pesticides 
  • Viruses
  • Cells

Published Papers (3 papers)

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Research

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15 pages, 2983 KiB  
Article
Metal Oxide Nanoparticle-Decorated Few Layer Graphene Nanoflake Chemoresistors for the Detection of Aromatic Volatile Organic Compounds
by Syrine Behi, Nadra Bohli, Juan Casanova-Cháfer, Eduard Llobet and Adnane Abdelghani
Sensors 2020, 20(12), 3413; https://doi.org/10.3390/s20123413 - 17 Jun 2020
Cited by 20 | Viewed by 3075
Abstract
Benzene, toluene, and xylene, commonly known as BTX, are hazardous aromatic organic vapors with high toxicity towards living organisms. Many techniques are being developed to provide the community with portable, cost effective, and high performance BTX sensing devices in order to effectively monitor [...] Read more.
Benzene, toluene, and xylene, commonly known as BTX, are hazardous aromatic organic vapors with high toxicity towards living organisms. Many techniques are being developed to provide the community with portable, cost effective, and high performance BTX sensing devices in order to effectively monitor the quality of air. In this paper, we study the effect of decorating graphene with tin oxide (SnO2) or tungsten oxide (WO3) nanoparticles on its performance as a chemoresistive material for detecting BTX vapors. Transmission electron microscopy and environmental scanning electron microscopy are used as morphological characterization techniques. SnO2-decorated graphene displayed high sensitivity towards benzene, toluene, and xylene with the lowest tested concentrations of 2 ppm, 1.5 ppm, and 0.2 ppm, respectively. In addition, we found that, by employing these nanomaterials, the observed response could provide a unique double signal confirmation to identify the presence of benzene vapors for monitoring occupational exposure in the textiles, painting, and adhesives industries or in fuel stations. Full article
(This article belongs to the Special Issue Nanomaterials for Chemical Sensors)
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11 pages, 3965 KiB  
Article
Cancer-Specific hNQO1-Responsive Biocompatible Naphthalimides Providing a Rapid Fluorescent Turn-On with an Enhanced Enzyme Affinity
by Sun Young Park, Eugeine Jung, Jong Seung Kim, Sung-Gil Chi and Min Hee Lee
Sensors 2020, 20(1), 53; https://doi.org/10.3390/s20010053 - 20 Dec 2019
Cited by 16 | Viewed by 3893
Abstract
Human NAD(P)H:quinone oxidoreductase 1 (hNQO1) is overexpressed in cancer cells and associated with the drug resistance factor of cancer. The objective of this work is the development of fluorescent probes for the efficient detection of hNQO1 activity in cancer cells, which can be [...] Read more.
Human NAD(P)H:quinone oxidoreductase 1 (hNQO1) is overexpressed in cancer cells and associated with the drug resistance factor of cancer. The objective of this work is the development of fluorescent probes for the efficient detection of hNQO1 activity in cancer cells, which can be employed for the cancer diagnosis and therapeutic agent development. Herein, we report naphthalimide-based fluorescent probes 1 and 2 that can detect hNQO1. For hNQO1 activity, the probes showed a significant fluorescence increase at 540 nm. In addition, probe 1, the naphthalimide containing a triphenylphosphonium salt, showed an enhanced enzyme efficiency and rapid detection under a physiological condition. The detection ability of probe 1 was superior to that of other previously reported probes. Moreover, probe 1 was less cytotoxic during the cancer cell imaging and readily provided a strong fluorescence in hNQO1-overexpressed cancer cells (A549). We proposed that probe 1 can be used to detect hNQO1 expression in live cells and it will be applied to develop the diagnosis and customized treatment of hNQO1-related disease. Full article
(This article belongs to the Special Issue Nanomaterials for Chemical Sensors)
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Review

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20 pages, 8341 KiB  
Review
Chiral Plasmonics and Their Potential for Point-of-Care Biosensing Applications
by Willian A. Paiva-Marques, Faustino Reyes Gómez, Osvaldo N. Oliveira, Jr. and J. Ricardo Mejía-Salazar
Sensors 2020, 20(3), 944; https://doi.org/10.3390/s20030944 - 10 Feb 2020
Cited by 31 | Viewed by 6761
Abstract
There has been growing interest in using strong field enhancement and light localization in plasmonic nanostructures to control the polarization properties of light. Various experimental techniques are now used to fabricate twisted metallic nanoparticles and metasurfaces, where strongly enhanced chiral near-fields are used [...] Read more.
There has been growing interest in using strong field enhancement and light localization in plasmonic nanostructures to control the polarization properties of light. Various experimental techniques are now used to fabricate twisted metallic nanoparticles and metasurfaces, where strongly enhanced chiral near-fields are used to intensify circular dichroism (CD) signals. In this review, state-of-the-art strategies to develop such chiral plasmonic nanoparticles and metasurfaces are summarized, with emphasis on the most recent trends for the design and development of functionalizable surfaces. The major objective is to perform enantiomer selection which is relevant in pharmaceutical applications and for biosensing. Enhanced sensing capabilities are key for the design and manufacture of lab-on-a-chip devices, commonly named point-of-care biosensing devices, which are promising for next-generation healthcare systems. Full article
(This article belongs to the Special Issue Nanomaterials for Chemical Sensors)
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