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Recent Advances in Apta-Biosensors
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Recent Advances in Apta-Biosensors

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".

Deadline for manuscript submissions: closed (31 August 2022) | Viewed by 12753

Special Issue Editors

Prof. Dr. Donghwan Kim

E-Mail Website1 Website2
Guest Editor
School of Chemical Engineering, Sungkyunkwan University (SKKU)
Interests: sensors; optical materials; nanophotonics; nanotechnology
Dr. Samy M. Shaban

E-Mail Website
Guest Editor
School of Chemical Engineering, Sungkyunkwan University (SKKU), Seoul, Republic of Korea
Interests: chemical sensor; bio-sensor; nanotechnology; surfactant technology; corrosion; catalysis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear colleagues,

The amazing and rapid scientific development in nanotechnology has made a breakthrough in the field of chemical and biological sensors. Sensor development is considered to be one of the most important aspects of scientific progress because of its impact on preserving the environment and human health, in addition to the economic aspect. The sensors can be used to detect pollutants, toxic heavy metals, or even biomarkers for many infectious and epidemic diseases.

The development of biosensor technology has attracted great attention as a method of analysis and diagnosis. It must meet points of care requirements such as being a fast, simple, selective, and low-cost method of analysis and diagnosis. Nanotechnology provides great progress in the field of sensors due to its higher surface area to volume ratio, optical properties, biocompatibility, and ability to manifest biological signaling and transduction mechanisms.

The aim of this Special Issue is to collect recent progress and development in biosensor technology describing biomarkers and toxic materials assays. The Special Issue welcomes papers, communications, and reports covering topics that include but are not limited to the following:

Apta-Biosensor progress

Chemical sensor development

Point-of-care testing

Optical biosensor

Biomarkers assay

Nanotechnology

Bio-sensor applications

Solid-based biosensor

Fluorometric biosensor

Prof. Dr. Donghwan Kim
Dr. Samy M. Shaban
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Apta-Biosensor progress
  • Chemical sensor development
  • Point-of-care testing
  • Optical biosensor
  • Biomarkers assay
  • Nanotechnology
  • Bio-sensor applications
  • Solid-based biosensor
  • Fluorometric biosensor

Published Papers (2 papers)

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Research

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11 pages, 1924 KiB  
Article
Establishment of an Improved ELONA Method for Detecting Fumonisin B1 Based on Aptamers and Hemin-CDs Conjugates
by Xinyue Zhao, Jiale Gao, Yuzhu Song, Jinyang Zhang and Qinqin Han
Sensors 2022, 22(17), 6714; https://doi.org/10.3390/s22176714 - 05 Sep 2022
Cited by 3 | Viewed by 1764
Abstract
Fumonisin B1 (FB1) is a strong mycotoxin that is ubiquitous in agricultural products. The establishment of rapid detection methods is an important means to prevent and control FB1 contamination. In this study, an improved enzyme-linked oligonucleotide assay (ELONA) method [...] Read more.
Fumonisin B1 (FB1) is a strong mycotoxin that is ubiquitous in agricultural products. The establishment of rapid detection methods is an important means to prevent and control FB1 contamination. In this study, an improved enzyme-linked oligonucleotide assay (ELONA) method was designed and tested to detect the contents of FB1 in maize (corn) samples. F10 modified with biotin was bound to an enzyme label plate that was coated with streptavidin (SA) in advance, and carbon dots (CDs) were used to catalyze the color of tetramethylbenzidine (TMB). The complementary chain of F10 was modified with an amino group and coupled with CDs to obtain conjugates. The sample and conjugates were then added to the enzyme plate coated with F10 (an FB1 aptamer). Upon completion of the color reaction, the absorbance was measured at 450 nm. The LOD of this method was 4.30 ng/mL and the LOQ was 13.03 ng/mL. We observed a linear relationship in the FB1 concentration range of 0–100 ng/mL. The standard curve was y = −0.001482 × x + 0.3463, R2 = 0.9918, and the experimental results could be directly measured visually. The recovery of the maize sample was 97.5–99.23% and 94.54–99.25%, and the total detection time was 1 h. Full article
(This article belongs to the Special Issue Recent Advances in Apta-Biosensors)
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Review

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31 pages, 11577 KiB  
Review
Recent Advances in Aptamer Sensors
by Samy M. Shaban and Dong-Hwan Kim
Sensors 2021, 21(3), 979; https://doi.org/10.3390/s21030979 - 02 Feb 2021
Cited by 54 | Viewed by 9908
Abstract
Recently, aptamers have attracted attention in the biosensing field as signal recognition elements because of their high binding affinity toward specific targets such as proteins, cells, small molecules, and even metal ions, antibodies for which are difficult to obtain. Aptamers are single oligonucleotides [...] Read more.
Recently, aptamers have attracted attention in the biosensing field as signal recognition elements because of their high binding affinity toward specific targets such as proteins, cells, small molecules, and even metal ions, antibodies for which are difficult to obtain. Aptamers are single oligonucleotides generated by in vitro selection mechanisms via the systematic evolution of ligand exponential enrichment (SELEX) process. In addition to their high binding affinity, aptamers can be easily functionalized and engineered, providing several signaling modes such as colorimetric, fluorometric, and electrochemical, in what are known as aptasensors. In this review, recent advances in aptasensors as powerful biosensor probes that could be used in different fields, including environmental monitoring, clinical diagnosis, and drug monitoring, are described. Advances in aptamer-based colorimetric, fluorometric, and electrochemical aptasensing with their advantages and disadvantages are summarized and critically discussed. Additionally, future prospects are pointed out to facilitate the development of aptasensor technology for different targets. Full article
(This article belongs to the Special Issue Recent Advances in Apta-Biosensors)
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