Recent Progress in Polymer Based Hybrid Nanocomposites toward Tailoring Advanced Applications

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Polymer Applications".

Deadline for manuscript submissions: closed (30 September 2021) | Viewed by 3535

Special Issue Editor

Special Issue Information

Dear Colleagues,

Organic/inorganic hybrid nanocomposites, specifically polymer-based hybrid nanocomposites, represent rising advanced materials since they mix distinctive properties from the inorganic and organic (i.e., polymeric) components. In recent years, an incredible amount of attention has been given to the event of materials for economical energy harvesting; polymer-based hybrid materials have additionally been gaining vital advances to supply pollutant-free drinking water, sensing of environmental pollutants, energy storage, and conservation.

The aim and scope of this Special Issue is to provide a probe medium and a vital foundation for the advancement and dissemination of research results that support recent progress within the development of polymer-based hybrid nanocomposite properties, fabrication strategies, and their various applications for environmental remediation, such as treatment of contaminants, pollutant sensing and detection, etc.

This exclusive issue will offer a contemporary look into how polymer nanocomposites can be used in environmental remediation, detailing essential environmental issues and key material properties and current polymers or nanomaterials that can solve these issues. The issue covers the essential molecular structure of polymers used in environmental applications, the toxicology, economy, and lifecycle analysis of polymer nanocomposites, and an analysis of viable future applications of these materials.

We are initiating a Call for Papers for researchers who are interested in presenting new research work on polymer-based hybrid nanocomposites toward tailoring advanced applications. Such excellent works on polymer-based hybrid nanocomposites deserve high visibility and their presentation in open access journals, such as Polymers MDPI. This Special Issue will include high-quality articles by internationally recognized scholars. We invite materials scientists, nanotechnologists, chemical and polymer science engineers, and scientists in the related fields of engineering and technology to participate through the submission of research/review/short communication articles covering (but not limited to) the following topics:

  • Polymer/layered silicate hybrid nanocomposites;
  • Graphene oxide containing polymer hybrid nanocomposites;
  • Polymer–ceramic hybrid nanocomposites;
  • Advanced application of polymer-based hybrid nanocomposites for development of advanced lithium batteries, supercapacitor, solar energy applications, etc.;
  • Drug delivery and nanohydrogel;
  • Biodegradable polymer-based nanoadsorbents for environmental remediation;
  • Bionanocomposites: green materials for a sustainable future;
  • Application of polymer-based hybrid nanocomposites in water purification;
  • Preparation, properties, and application of polymer-based hybrid nanocomposites in sensing of environmental pollutants;
  • Development of hybrid fillers/polymer nanocomposites for electronic applications;
  • High performance hybrid filler reinforced epoxy nanocomposites;
  • State-of-the-art overview of elastomer/hybrid filler nanocomposites;
  • Polymer nanocomposites and related legal issues;
  • Supports further technological developments by discussing both theory and real-world experimental data from academia and industry.

Prof. Dr. Sadanand Pandey
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Organic–inorganic hybrid
  • Advanced polymer composites
  • Hydrogels
  • Polymer–fiber interphase
  • Shape–memory polymer nanocomposites
  • Multifunctional interfaces
  • Smart nanocomposites
  • Wastewater treatment
  • Nanocomposites for CO2 storage and conversion

Published Papers (1 paper)

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Research

23 pages, 8194 KiB  
Article
Simulation, In Vitro, and In Vivo Cytotoxicity Assessments of Methotrexate-Loaded pH-Responsive Nanocarriers
by Mahmood Barani, Mohammad Reza Hajinezhad, Saman Sargazi, Mahira Zeeshan, Abbas Rahdar, Sadanand Pandey, Mehrdad Khatami and Farshid Zargari
Polymers 2021, 13(18), 3153; https://doi.org/10.3390/polym13183153 - 17 Sep 2021
Cited by 29 | Viewed by 2873
Abstract
In this study, pH-responsive niosomal methotrexate (MTX) modified with ergosterol was prepared for potential anticancer application. The prepared formulation had a size of 176.7 ± 3.4 nm, zeta potential of −31.5 ± 2.6 mV, EE% of 76.9 ± 2.5%, and a pH-responsive behavior [...] Read more.
In this study, pH-responsive niosomal methotrexate (MTX) modified with ergosterol was prepared for potential anticancer application. The prepared formulation had a size of 176.7 ± 3.4 nm, zeta potential of −31.5 ± 2.6 mV, EE% of 76.9 ± 2.5%, and a pH-responsive behavior in two different pHs (5.4 and 7.4). In-silico evaluations showed that MTX intended to make a strong hydrogen bond with Span 60 compartments involving N2 and O4 atoms in glutamic acid and N7 atom in pteridine ring moieties, respectively. The cytotoxic effects of free and pH-MTX/Nio were assessed against MCF7 and HUVECs. Compared with free MTX, we found significantly lower IC50s when MCF7 cells were treated with niosomal MTX (84.03 vs. 9.464 µg/mL after 48 h, respectively). Moreover, lower cell killing activity was observed for this formulation in normal cells. The pH-MTX/Nio exhibited a set of morphological changes in MCF7 cells observed during cell death. In-vivo results demonstrated that intraperitoneal administration of free MTX (2 mg/kg) after six weeks caused a significant increase in serum blood urea nitrogen (BUN), serum creatinine, and serum malondialdehyde (MDA) levels of rats compared to the normal control rats. Treatment with 2 and 4 mg/kg doses of pH-MTX/Nio significantly increased serum BUN, serum creatinine, and serum lipid peroxidation. Still, the safety profile of such formulations in healthy cells/tissues should be further investigated. Full article
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