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Polymers
Special Issues
Recent Developments in Antimicrobial Polymers
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Recent Developments in Antimicrobial Polymers

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Biomacromolecules, Biobased and Biodegradable Polymers".

Deadline for manuscript submissions: closed (25 October 2023) | Viewed by 6081

Special Issue Editors

Dr. Jiquan Zhang

E-Mail Website
Guest Editor
School of Life Sciences, Hebei University, Baoding, China
Interests: crustacean; genome editing; antimicrobial peptide; functional genomics
Dr. Yuying Sun

E-Mail Website
Guest Editor
School of Life Sciences, Hebei University, Baoding, China
Interests: antimicrobial peptide; functional genomics; fermentation engineering

Special Issue Information

Dear Colleagues,

This Special Issue on Recent Developments in Antimicrobial Polymers is devoted to disseminating contributions concerning the synthesis and function of antimicrobial polymers.

Microbes are a ubiquitous threat around the world and pose a serious danger to people's life. However, small molecules soluble in water and traditional antimicrobial agents often suffer from residual toxicity. In recent years, antimicrobial polymers have received considerable attention from researchers for their high biocompatibility, stronger and longer antimicrobial activity, and non-toxic properties. The large class of antimicrobial macromolecular systems, polymers, and copolymers have been rigorously developed, and many antimicrobial polymers have been applied in medical treatment, food, and textile industries. With our further understanding of the antibacterial mechanism and the development of polymer materials, it is possible to design and synthesize specific macromolecules with enhanced selectivity and antibacterial activity. The application of antimicrobial polymers will be expanded to more fields.

Thus, any original contributions and comprehensive reviews referring to antimicrobial polymer’s construction, antimicrobial peptides or antibiotics, biocidal polymers, antimicrobial mechanisms and applications are welcome

Dr. Jiquan Zhang
Dr. Yuying Sun
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antibacterial peptide
  • metabolic engineering of antibiotics
  • biocidal polymers
  • antimicrobial material
  • synthetic mimic

Published Papers (3 papers)

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Research

18 pages, 6110 KiB  
Article
The Antibacterial Activities and Characterizations of Biosynthesized Zinc Oxide Nanoparticles, and Their Coated with Alginate Derived from Fucus vesiculosus
by Ragaa A. Hamouda, Asrar A. Alharbi, Majdah M. Al-Tuwaijri and Rabab R. Makharita
Polymers 2023, 15(10), 2335; https://doi.org/10.3390/polym15102335 - 17 May 2023
Cited by 5 | Viewed by 1652
Abstract
Zinc oxide nanoparticles have many advantages for nano-biotechnologists due to their intense biomedical applications. ZnO-NPs are used as antibacterial agents, which influence bacterial cells through the rupture of the cell membrane and the generation of reactive free radicals. Alginate is a polysaccharide of [...] Read more.
Zinc oxide nanoparticles have many advantages for nano-biotechnologists due to their intense biomedical applications. ZnO-NPs are used as antibacterial agents, which influence bacterial cells through the rupture of the cell membrane and the generation of reactive free radicals. Alginate is a polysaccharide of natural origin due to its excellent properties that are used in various biomedical applications. Brown algae are good sources of alginate and are used as a reducing agent in the synthesis of nanoparticles. This study aims to synthesize ZnO-NPs by using brown alga Fucus vesiculosus (Fu/ZnO-NPs) and also to extract alginate from the same alga, which is used in coating the ZnO-NPs (Fu/ZnO-Alg-NCMs). The characterizations of Fu/ZnO-NPs and Fu/ZnO-Alg-NCMs were determined by FTIR, TEM, XRD, and zeta potential. The antibacterial activities were applied against multidrug resistance bacteria of both gram-positive and negative. The results obtained in FT-TR showed there are some shifts in the peak positions of Fu/ZnO-NPs and Fu/ZnO-Alg-NCMs. The peak at 1655 cm−1, which assigned amide I-III, is present in both Fu/ZnO-NPs and Fu-Alg-ZnO-NCMs; this band is responsible for bio-reductions and stabilization of both nanoparticles. The TEM images proved the Fu/ZnO-NPs have rod shapes with sizes ranging from 12.68 to 17.66 and are aggregated, but Fu/ZnO/Alg-NCMs are spherical in shape with sizes ranging from 12.13 to 19.77. XRD-cleared Fu/ZnO-NPs have nine sharp peaks that are considered good crystalline, but Fu/ZnO-Alg-NCMs have four broad and sharp peaks that are considered semi-crystalline. Both Fu/ZnO-NPs and Fu/ZnO-Alg-NCMs have negative charges (−1.74 and −3.56, respectively). Fu/ZnO-NPs have more antibacterial activities than Fu/ZnO/Alg-NCMs in all tested multidrug-resistant bacterial strains. Fu/ZnO/Alg-NCMs had no effect on Acinetobacter KY856930, Staphylococcus epidermidis, and Enterobacter aerogenes, whereas there was an apparent effect of ZnO-NPs against the same strains. Full article
(This article belongs to the Special Issue Recent Developments in Antimicrobial Polymers)
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15 pages, 9356 KiB  
Article
Preparation and Mechanism of Bio-Based Sodium Alginate Fibers with Flame Retardant and Antibacterial Properties
by Jiamin Xu, Zhenlin Jiang, Fang Hou, Keyu Zhu, Chenxue Xu, Chaosheng Wang and Huaping Wang
Polymers 2023, 15(1), 154; https://doi.org/10.3390/polym15010154 - 29 Dec 2022
Cited by 4 | Viewed by 2401
Abstract
Flame retardant and antibacterial sodium alginate (SA) fiber were fabricated using the bio-based flame retardant of phytic acid and DL-arginine successively, and then the morphological structures, combustion behavior, thermal stability, and mechanical as well as antibacterial properties of SA fiber were investigated carefully. [...] Read more.
Flame retardant and antibacterial sodium alginate (SA) fiber were fabricated using the bio-based flame retardant of phytic acid and DL-arginine successively, and then the morphological structures, combustion behavior, thermal stability, and mechanical as well as antibacterial properties of SA fiber were investigated carefully. It is found that when the additional amount of PADL (reaction products of phytic acid and DL-arginine) in SA composite fiber is 20 wt%, its limiting oxygen index (LOI) is 40.0 ± 0.3%, and UL−94 is V−0 grade. The combustion behavior of composite fiber shows that PADL can effectively reduce combustion heat and promote carbon formation. Its peak of HRR (pkHRR) is 5.9% of pure SA fiber, and the residual carbon increases from 23.0 ± 0.1% to 44.2 ± 0.2%. At the same time, the density of the residual carbon increases gradually. PADL can promote SA to form expanded carbon with increasing density, and isolate the heat and volatilization of combustible gases. The guanidine group of DL-arginine can interact with the cell membrane to kill bacteria, and the antibacterial property of SA composite fiber is increased by 30%. This study provides a very ecological, safe, environmentally friendly and simple method to prepare flame retardant and antibacterial SA composite fiber with bio-based materials. Full article
(This article belongs to the Special Issue Recent Developments in Antimicrobial Polymers)
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11 pages, 1645 KiB  
Article
Biocidal Coatings from Complexes of Carboxylated Latex Particles and a Linear Cationic Polymer
by Irina G. Panova, Evgeniya A. Shevaleva, Inessa A. Gritskova, Nataliya G. Loiko, Yury A. Nikolaev, Olga A. Novoskoltseva and Alexander A. Yaroslavov
Polymers 2022, 14(21), 4598; https://doi.org/10.3390/polym14214598 - 29 Oct 2022
Cited by 5 | Viewed by 1310
Abstract
A linear polycation, poly(diallyldimethylammonium chloride), electrostatically interacts with anionic latex particles from a carboxylated butadiene–styrene copolymer in aqueous solution thus forming an interpolyelectrolyte complex. A mutual neutralization of oppositely charged latex and polycation groups occurs at W = latex/polycation = 50 w/w ratio. [...] Read more.
A linear polycation, poly(diallyldimethylammonium chloride), electrostatically interacts with anionic latex particles from a carboxylated butadiene–styrene copolymer in aqueous solution thus forming an interpolyelectrolyte complex. A mutual neutralization of oppositely charged latex and polycation groups occurs at W = latex/polycation = 50 w/w ratio. At W = 27, an ultimate polycation adsorption is reached, resulting in the formation of positive polycomplex particles, while at W ˂ 27, two-component systems are formed composed of positive polycomplex particles and free polycation. A film created from the W = 12 formulation shows a high toxicity to Gram-positive and Gram-negative bacteria and yeast. Repeated washing the film leads to partial removal of polycation and a 50% decrease in the activity of the film only towards Gram-negative Pseudomonas aeruginosa. The results indicate the potential for use of the mixed polymer formulations for the fabrication of antimicrobial films and coatings. Full article
(This article belongs to the Special Issue Recent Developments in Antimicrobial Polymers)
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