Advance in Molecularly Imprinted Polymers II

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Polymer Applications".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 3758

Special Issue Editor


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Guest Editor
Supramolecular Chemistry Group, Faculty of Chemistry, Adam Mickiewicz University, Poznań, Poland
Interests: materiel characterization; nanomaterials sunthesis; molecularly imprinted polymers
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Special Issue Information

Dear Colleagues,

Molecularly imprinted polymers (MIPs) are undoubtedly an exciting class of polymers, as they possess antibody-like affinity towards particular molecules. Due to their very high selectivity, MIPs possess cavities that are complementary to template molecules with regard to size, shape, and presence of particular functional groups. The advantage of MIPs over natural antibodies is their high thermal and chemical stability, excellent reusability, and easy, low-cost synthesis. As a result, MIPs have been widely used as artificial receptors for separation purposes, as sensors, to promote catalysis, during drug development, and for screening. MIPs can be produced for various target molecules, in contrast to biological receptors, where the target must match an available antibody.

This Special Issue invites original papers and reviews that report on the recent progress in MIP chemistry, which includes the following topics:

  • Novel MIP synthesis methods;
  • Examination of interactions formed by MIPs;
  • MIP application in separation, drug delivery, catalysis and as sensors;
  • Novel MIP applications;
  • Synthesis of new MIP monomers;
  • Obtaining surface-imprinted materials;
  • Synthesis and application of imprinted hybrid materials.

Dr. Michał Cegłowski
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • molecularly imprinted polymers
  • molecular imprinting
  • molecular recognition
  • functional polymers
  • functional monomers
  • selective interactions
  • separation techniques
  • solid-phase extraction
  • drug delivery
  • sensing
  • ion imprinting

Published Papers (2 papers)

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Research

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17 pages, 2405 KiB  
Article
A Label-Free Electrochemical Biosensor for Homocysteine Detection Using Molecularly Imprinted Polymer and Nanocomposite-Modified Electrodes
by Unchalee Kongintr, Benchaporn Lertanantawong and Chamras Promptmas
Polymers 2023, 15(10), 2241; https://doi.org/10.3390/polym15102241 - 09 May 2023
Cited by 2 | Viewed by 1830
Abstract
An essential biomarker for the early detection of cardiovascular diseases is serum homocysteine (Hcy). In this study, a molecularly imprinted polymer (MIP) and nanocomposite were used to create a label-free electrochemical biosensor for reliable Hcy detection. A novel Hcy-specific MIP (Hcy-MIP) was synthesized [...] Read more.
An essential biomarker for the early detection of cardiovascular diseases is serum homocysteine (Hcy). In this study, a molecularly imprinted polymer (MIP) and nanocomposite were used to create a label-free electrochemical biosensor for reliable Hcy detection. A novel Hcy-specific MIP (Hcy-MIP) was synthesized using methacrylic acid (MAA) in the presence of trimethylolpropane trimethacrylate (TRIM). The Hcy-MIP biosensor was fabricated by overlaying the mixture of Hcy-MIP and the carbon nanotube/chitosan/ionic liquid compound (CNT/CS/IL) nanocomposite on the surface of a screen-printed carbon electrode (SPCE). It showed high sensitivity, with a linear response of 5.0 to 150 µM (R2 of 0.9753) and with a limit of detection (LOD) at 1.2 µM. It demonstrated low cross-reactivity with ascorbic acid, cysteine, and methionine. Recoveries of 91.10–95.83% were achieved when the Hcy-MIP biosensor was used for Hcy at 50–150 µM concentrations. The repeatability and reproducibility of the biosensor at the Hcy concentrations of 5.0 and 150 µM were very good, with coefficients of variation at 2.27–3.50% and 3.42–4.22%, respectively. This novel biosensor offers a new and effective method for Hcy assay compared with the chemiluminescent microparticle immunoassay at the correlation coefficient (R2) of 0.9946. Full article
(This article belongs to the Special Issue Advance in Molecularly Imprinted Polymers II)
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Review

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46 pages, 4873 KiB  
Review
Recent Developments in the Detection of Organic Contaminants Using Molecularly Imprinted Polymers Combined with Various Analytical Techniques
by Tomasz Nazim, Aleksandra Lusina and Michał Cegłowski
Polymers 2023, 15(19), 3868; https://doi.org/10.3390/polym15193868 - 24 Sep 2023
Viewed by 1448
Abstract
Molecularly imprinted polymers (MIPs) encompass a diverse array of polymeric matrices that exhibit the unique capacity to selectively identify a designated template molecule through specific chemical moieties. Thanks to their pivotal attributes, including exceptional selectivity, extended shelf stability, and other distinct characteristics, this [...] Read more.
Molecularly imprinted polymers (MIPs) encompass a diverse array of polymeric matrices that exhibit the unique capacity to selectively identify a designated template molecule through specific chemical moieties. Thanks to their pivotal attributes, including exceptional selectivity, extended shelf stability, and other distinct characteristics, this class of compounds has garnered interest in the development of highly responsive sensor systems. As a result, the incorporation of MIPs in crafting distinctive sensors and analytical procedures tailored for specific analytes across various domains has increasingly become a common practice within contemporary analytical chemistry. Furthermore, the range of polymers amenable to MIP formulation significantly influences the potential utilization of both conventional and innovative analytical methodologies. This versatility expands the array of possibilities in which MIP-based sensing can be employed in recognition systems. The following review summarizes the notable progress achieved within the preceding seven-year period in employing MIP-based sensing techniques for analyte determination. Full article
(This article belongs to the Special Issue Advance in Molecularly Imprinted Polymers II)
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