Therapeutic Potential of Plant-Derived Bioactive Compounds in Non-Communicable Diseases

A special issue of Plants (ISSN 2223-7747).

Deadline for manuscript submissions: 15 May 2024 | Viewed by 1445

Special Issue Editor


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Guest Editor
Heart, Mind & Body Research Group, Griffith University, Gold Coast, QLD 4222, Australia
Interests: health promotion; maternal and child health; non-communicable disease prevention; gut microbiota in health and disease; nutrition-related behaviour change theories; determinants of dietary patterns; polyphenols/flavonoids and human health; epidemiological data analysis
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Special Issue Information

Dear Colleagues,

Plant-based foods and/or medicinal plants can provide us with a plethora of natural bioactive compounds. The types and levels of bioactive compounds vary in plants depending on their species, latitude, geographical origin, cultivation conditions and ripeness stage. The main bioactive compounds identified in plants are polyphenols, carotenoids, tocopherols, phytosterols, and other classes. Bioactive compounds have therapeutic potential against certain chronic diseases, as demonstrated by in vivo/vitro models. However, there is need to explore potential molecular mechanisms of bioactive compounds with regard to their preventive/therapeutic effects against non-communicable diseases (NCDs) such as cancer, cardiovascular disease, obesity, diabetes, neurodegenerative disorders, and many others.

Thus, this Special Issue focuses on the role of plant-derived bioactive compounds in the treatment of NCDs. We cordially invite researchers from around the world to submit both experimental and review articles addressing the potential molecular mechanisms by which bioactive compounds from plants-based foods and medicinal plants exert antioxidant and/or anti-inflammatory activities with therapeutic potential in NCDs.

Dr. Naser Alsharairi
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Plants is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bioactive compounds
  • plant-based foods
  • medicinal plants
  • molecular mechanisms
  • anti-inflammatory activity
  • antioxidant activity
  • clinical and pre-clinical studies
  • in vivo/vitro models
  • phytochemical analysis/evaluation

Published Papers (1 paper)

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Review

15 pages, 308 KiB  
Review
Experimental Studies on the Therapeutic Potential of Vaccinium Berries in Breast Cancer—A Review
by Naser A. Alsharairi
Plants 2024, 13(2), 153; https://doi.org/10.3390/plants13020153 - 05 Jan 2024
Cited by 1 | Viewed by 1030
Abstract
Breast cancer (BC) is the largest contributor to cancer deaths in women worldwide. Various parts of plants, including fruits, are known for their therapeutic properties and are used in traditional medicine. Fruit species exhibit anticancer activities due to the presence of bioactive natural [...] Read more.
Breast cancer (BC) is the largest contributor to cancer deaths in women worldwide. Various parts of plants, including fruits, are known for their therapeutic properties and are used in traditional medicine. Fruit species exhibit anticancer activities due to the presence of bioactive natural compounds such as flavonoids and carotenoids. The Vaccinium spp. are fleshy berry-like drupes and are rich in bioactive compounds, with flavonols, flavanols, chalcones, and phenolic acids as the major groups of compounds. While there is clear evidence linking Vaccinium berries with a decreased risk of BC both in in vivo and in vitro experiments, the exact mechanisms involved in the protective effects of Vaccinium spp. rich extracts on BC cells are not fully understood. Thus, the purpose of this review is to highlight the mechanisms of action involved in the therapeutic potential of Vaccinium berries against BC in experimental models. Full article
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