Bioactive Compounds in Plants—2nd Edition

A special issue of Plants (ISSN 2223-7747). This special issue belongs to the section "Phytochemistry".

Deadline for manuscript submissions: 30 August 2024 | Viewed by 741

Special Issue Editors


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Guest Editor
Plant Biology Department, Faculty of Biology, University of Murcia, Campus de Espinardo, E-30100 Murcia, Spain
Interests: Elicitation, plant in vitro cultures, specialized metabolism, plant defense responses, plant by-products, biostimulants
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Plant Biology Department, Faculty of Biology, University of Murcia, Campus de Espinardo, E-30100 Murcia, Spain
Interests: Elicitation, plant in vitro cultures, specialized metabolism, plant defense responses, plant by-products, biostimulants
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Plant bioactive compounds comprise valuable plant components with diverse functions, acting as the defense mechanisms of plants under stress situations. Moreover, the high added value of these bioactive compounds is based on their enormous pharmaceutical interest since some of them possess biological properties relevant for human health such as antioxidant, antimicrobial, and anticancer activities. The great biological importance of these compounds contradicts their small quantities found in plants, making their extraction a very expensive process. Moreover, many of these compounds have not been completely characterized, and achieving their high extraction yields has not been accomplished yet. The aim of this Special Issue is to gather original research papers, along with review articles, focusing on the recent advances in the field of plant bioactive compounds. This Special Issue of Plants will cover a wide variety of topics, including extraction and identification techniques, bioactivity assays, molecular approaches, and biotechnological strategies to obtain bioactive compounds from plants.

Dr. Sabater-Jara Ana Belén
Dr. Lorena Almagro
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Plants is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • specialized metabolism
  • plant defense responses
  • plant by-products
  • biostimulants
  • biological activity
  • extraction and identification methods

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Published Papers (1 paper)

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Research

20 pages, 2214 KiB  
Article
Eucalypt Extracts Prepared by a No-Waste Method and Their 3D-Printed Dosage Forms Show Antimicrobial and Anti-Inflammatory Activity
by Oleh Koshovyi, Mykola Komisarenko, Tatyana Osolodchenko, Andrey Komissarenko, Reet Mändar, Siiri Kõljalg, Jyrki Heinämäki and Ain Raal
Plants 2024, 13(6), 754; https://doi.org/10.3390/plants13060754 - 07 Mar 2024
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Abstract
The pharmaceutical industry usually utilizes either hydrophobic or hydrophilic substances extracted from raw plant materials to prepare a final product. However, the waste products from the plant material still contain biologically active components with the opposite solubility. The aim of this study was [...] Read more.
The pharmaceutical industry usually utilizes either hydrophobic or hydrophilic substances extracted from raw plant materials to prepare a final product. However, the waste products from the plant material still contain biologically active components with the opposite solubility. The aim of this study was to enhance the comprehensive usability of plant materials by developing a new no-waste extraction method for eucalypt leaves and by investigating the phytochemical and pharmacological properties of eucalypt extracts and their 3D-printed dosage forms. The present extraction method enabled us to prepare both hydrophobic soft extracts and hydrophilic (aqueous) dry extracts. We identified a total of 28 terpenes in the hydrophobic soft extract. In the hydrophilic dry extract, a total of 57 substances were identified, and 26 of them were successfully isolated. The eucalypt extracts studied showed significant antimicrobial activity against Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus subtilis, Candida albicans, Corynebacterium diphtheriae gravis, and Corynebacterium diphtheriae mitis. The anti-inflammatory activity of the dry extract was studied using a formalin-induced-edema model in mice. The maximum anti-exudative effect of the dry extract was 61.5% at a dose of 20 mg/kg. Composite gels of polyethylene oxide (PEO) and eucalypt extract were developed, and the key process parameters for semi-solid extrusion (SSE) 3D printing of such gels were verified. The SSE 3D-printed preparations of novel synergistically acting eucalypt extracts could have uses in antimicrobial and anti-inflammatory medicinal applications. Full article
(This article belongs to the Special Issue Bioactive Compounds in Plants—2nd Edition)
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