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Pharmaceutics
Special Issues
Novel Drug Delivery Nanosystems for Cancer Therapy and Bio-Regeneration
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Novel Drug Delivery Nanosystems for Cancer Therapy and Bio-Regeneration

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".

Deadline for manuscript submissions: closed (10 December 2023) | Viewed by 7632

Special Issue Editors

Prof. Dr. José Manuel Peula-García

E-Mail Website
Guest Editor
1. Biocolloid and Fluid Physics Group, Department of Applied Physics, University of Granada, 18071 Granada, Spain
2. Department of Applied Physics II, University of Málaga, 29071 Málaga, Spain
Interests: drug delivery; tissue engineering; polymeric nanoparticles; lipid nanocapsules
Prof. Dr. Juan Antonio Marchal Corrales

E-Mail Website
Guest Editor
Biopathology and Regenerative Medicine Institute (IBIMER), Centre for Biomedical Research, University of Granada, 18100 Granada, Spain
Interests: cancer therapy; nanotheranostics; nanoghosts; regenerative medicine; tissue engineering; drug delivery; extracellular vesicles; exosomes
Special Issues, Collections and Topics in MDPI journals
Dr. Ana Belén Jódar-Reyes

E-Mail Website
Guest Editor
Biocolloid and Fluid Physics Group, Department of Applied Physics, University of Granada, 18071 Granada, Spain
Interests: drug delivery; tissue engineering; polymeric nanoparticles; lipid nanocapsules; nanogels

Special Issue Information

Dear Colleagues,

Recent advances in nanotechnology applied to medicine have allowed for the development of different smart nanosystems as efficient carriers for the directed delivery of drugs and therapeutic biomolecules. Multidisciplinary research is necessary in order to evaluate the suitability of these systems from biological, physico-chemical, translational, and medical points of view. This Special Issue focuses on state-of-the-art efforts in the development of novel nanosystems useful in cancer therapy and in regenerative biomedicine or tissue engineering.

In particular, we welcome the submission of contributions dealing with one or more of the following areas:

  • Nanomedicines based on polymeric nanoparticles, lipid nanocapsules, nanofibers, magnetic nanocarriers, extracellular vesicles as therapeutics, nanotheranostics, and nanogels, analyzed from interdisciplinar perspectives. Thus, the formulation of physico-chemical characteristics, and biological or translational research including in vivo models, are of interest;
  • In addition, applications on several types of cancer or on several injuries susceptible of regeneration approaches are also welcome, with the aim of providing a complete state of the art and future directions in these fields.

Prof. Dr. José Manuel Peula-García
Prof. Dr. Juan Antonio Marchal Corrales
Dr. Ana Belén Jódar-Reyes
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • anticancer-drug delivery
  • regenerative medicine
  • tissue engineering
  • polymeric nanoparticles
  • lipid nanocapsules
  • nanofibers
  • nanotheranostics
  • extracellular vesicles
  • magnetic nanoparticles
  • nanogels

Published Papers (2 papers)

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Review

27 pages, 1142 KiB  
Review
Novel Drug Delivery Systems as an Emerging Platform for Stomach Cancer Therapy
by Umme Hani, Riyaz Ali M. Osmani, Sabina Yasmin, B. H. Jaswanth Gowda, Hissana Ather, Mohammad Yousuf Ansari, Ayesha Siddiqua, Mohammed Ghazwani, Adel Al Fatease, Ali H. Alamri, Mohamed Rahamathulla, M. Yasmin Begum and Shadma Wahab
Pharmaceutics 2022, 14(8), 1576; https://doi.org/10.3390/pharmaceutics14081576 - 29 Jul 2022
Cited by 24 | Viewed by 4313
Abstract
Cancer has long been regarded as one of the world’s most fatal diseases, claiming the lives of countless individuals each year. Stomach cancer is a prevalent cancer that has recently reached a high number of fatalities. It continues to be one of the [...] Read more.
Cancer has long been regarded as one of the world’s most fatal diseases, claiming the lives of countless individuals each year. Stomach cancer is a prevalent cancer that has recently reached a high number of fatalities. It continues to be one of the most fatal cancer forms, requiring immediate attention due to its low overall survival rate. Early detection and appropriate therapy are, perhaps, of the most difficult challenges in the fight against stomach cancer. We focused on positive tactics for stomach cancer therapy in this paper, and we went over the most current advancements and progressions of nanotechnology-based systems in modern drug delivery and therapies in great detail. Recent therapeutic tactics used in nanotechnology-based delivery of drugs aim to improve cellular absorption, pharmacokinetics, and anticancer drug efficacy, allowing for more precise targeting of specific agents for effective stomach cancer treatment. The current review also provides information on ongoing research aimed at improving the curative effectiveness of existing anti-stomach cancer medicines. All these crucial matters discussed under one overarching title will be extremely useful to readers who are working on developing multi-functional nano-constructs for improved diagnosis and treatment of stomach cancer. Full article
(This article belongs to the Special Issue Novel Drug Delivery Nanosystems for Cancer Therapy and Bio-Regeneration)
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20 pages, 2008 KiB  
Review
Progress and Hurdles of Therapeutic Nanosystems against Cancer
by Marina Martín-Contreras, Saúl A. Navarro-Marchal, José Manuel Peula-García and Ana Belén Jódar-Reyes
Pharmaceutics 2022, 14(2), 388; https://doi.org/10.3390/pharmaceutics14020388 - 10 Feb 2022
Cited by 3 | Viewed by 2378
Abstract
Nanomedicine against cancer, including diagnosis, prevention and treatment, has increased expectations for the solution of many biomedical challenges in the fight against this disease. In recent decades, an exhaustive design of nanosystems with high specificity, sensitivity and selectivity has been achieved due to [...] Read more.
Nanomedicine against cancer, including diagnosis, prevention and treatment, has increased expectations for the solution of many biomedical challenges in the fight against this disease. In recent decades, an exhaustive design of nanosystems with high specificity, sensitivity and selectivity has been achieved due to a rigorous control over their physicochemical properties and an understanding of the nano–bio interface. However, despite the considerable progress that has been reached in this field, there are still different hurdles that limit the clinical application of these nanosystems, which, along with their possible solutions, have been reviewed in this work. Specifically, physiological processes as biological barriers and protein corona formation related to the administration routes, designing strategies to overcome these obstacles, promising new multifunctional nanotherapeutics, and recent clinical trials are presented in this review. Full article
(This article belongs to the Special Issue Novel Drug Delivery Nanosystems for Cancer Therapy and Bio-Regeneration)
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