Polymers for Tissue Engineering and Biofabrication

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Smart and Functional Polymers".

Deadline for manuscript submissions: closed (15 June 2023) | Viewed by 3850

Special Issue Editors


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Guest Editor
Laboratory of Crystallographic Studies, Analusian Institute of Earth Science (CSIC), University of Granada, Armilla, Spain
Interests: nanocrystallization; bio-inspired crystallization; biomimetic scaffolds; biomaterials
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
1. Excellence Research Unit "Modeling Nature" (MNat), Biopathology and Medicine Regenerative Institute (IBIMER), University of Granada, Granada, Spain
2. Department of Human Anatomy and Embryology, University of Granada, Granada, Spain
3. Biosanitary Research Institute of Granada (ibs.GRANADA), Granada, Spain
Interests: biofabrication; organ on a chip; tissue engineering; cancer; regenerative medicine
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
1. Excellence Research Unit "Modeling Nature" (MNat), Department of Health Sciences, University of Jaén, Jaén, Spain
2. Biosanitary Research Institute of Granada (ibs.GRANADA), Granada, Spain
Interests: tissue engineering; regenerative medicine; biomaterials; bioinks; 3D bioprinting; decellularized matrix; stem cells
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The global demand for organ replacement or tissue regeneration is constantly increasing. Candidate target tissues for creating regenerative medicine products include bone, cartilage, vascular tissue, cornea or skin. Although tissue transplantation is readily available in many countries, the supply of tissue suitable for transplantation worldwide has never matched demand. Precision and personalized medicine is necessary for the treatment of highly prevalent tissue injuries, helping overcome the limitations of traditional medicine, generating biomimetic products that can help heal otherwise difficult-to-treat injuries. The feasibility of generating organized 3D tissue constructs combining cells and biomaterials has been demonstrated using a variety of biofabricated technologies. Biomaterials that can replicate the mechanical and biological properties of the target tissue are an essential component for the viable development of biofabricated technologies.

The aim of this Special Issue is to highlight the emerging research that is leading the way for the further development of useful materials for tissue engineering, tissue repair and regeneration. Additionally, special attention will be given to scaffold designs, fabrication methods such as 3D printing, and material–cell interactions, which are of great relevance to the structure and functionality of engineered tissue.

Dr. Jaime Gómez Morales
Dr. Juan Antonio Marchal Corrales
Dr. Elena López-Ruíz
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • functionalized polymeric materials
  • biomaterials
  • polymer engineering
  • 3D bioprinting
  • biofabrication
  • synthetic and natural biopolymers
  • decellularized matrix
  • tissue regeneration

Published Papers (1 paper)

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Review

28 pages, 11097 KiB  
Review
Eggshell Membrane as a Biomaterial for Bone Regeneration
by Adriana Torres-Mansilla, Maxwell Hincke, Ana Voltes, Elena López-Ruiz, Paula Alejandra Baldión, Juan Antonio Marchal, Pedro Álvarez-Lloret and Jaime Gómez-Morales
Polymers 2023, 15(6), 1342; https://doi.org/10.3390/polym15061342 - 08 Mar 2023
Cited by 9 | Viewed by 5420
Abstract
The physicochemical features of the avian eggshell membrane play an essential role in the process of calcium carbonate deposition during shell mineralization, giving rise to a porous mineralized tissue with remarkable mechanical properties and biological functions. The membrane could be useful by itself [...] Read more.
The physicochemical features of the avian eggshell membrane play an essential role in the process of calcium carbonate deposition during shell mineralization, giving rise to a porous mineralized tissue with remarkable mechanical properties and biological functions. The membrane could be useful by itself or as a bi-dimensional scaffold to build future bone-regenerative materials. This review focuses on the biological, physical, and mechanical properties of the eggshell membrane that could be useful for that purpose. Due to its low cost and wide availability as a waste byproduct of the egg processing industry, repurposing the eggshell membrane for bone bio-material manufacturing fulfills the principles of a circular economy. In addition, eggshell membrane particles have has the potential to be used as bio-ink for 3D printing of tailored implantable scaffolds. Herein, a literature review was conducted to ascertain the degree to which the properties of the eggshell membrane satisfy the requirements for the development of bone scaffolds. In principle, it is biocompatible and non-cytotoxic, and induces proliferation and differentiation of different cell types. Moreover, when implanted in animal models, it elicits a mild inflammatory response and displays characteristics of stability and biodegradability. Furthermore, the eggshell membrane possesses a mechanical viscoelastic behavior comparable to other collagen-based systems. Overall, the biological, physical, and mechanical features of the eggshell membrane, which can be further tuned and improved, make this natural polymer suitable as a basic component for developing new bone graft materials. Full article
(This article belongs to the Special Issue Polymers for Tissue Engineering and Biofabrication)
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