Targeted Drug Delivery for the Chronic Pain Treatment
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".
Deadline for manuscript submissions: closed (25 August 2022) | Viewed by 261
Special Issue Editors
Interests: interventional pain; pain management
Interests: neuromodulation; pain; discogenic pain; knee degenerative disease
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Complex chronic pain is a management challenge for primary care providers and physician pain specialists alike. When a chronic pain patient fails to respond to medication management, physical therapy, interventional pain procedures, and even surgeries, implantable pain control becomes a viable option with neurostimulation and targeted spinal drug delivery comprising the two widely available implantable options.
Pain pumps implanted for targeted spinal drug delivery have significantly higher risks compared to neurostimulation systems but are often more effective for the most complex pain problems—pain with nociceptive components, diffuse pain, cancer pain, and pain syndromes for which neurostimulation trials and/or implants have failed. While neurostimulation is widely practiced by many pain specialists worldwide, pain pumps are much less popular and are implanted and managed by a relatively small group of specialists. This Special Issue aims to examine the evidence basis for pain pumps and their effectiveness for a myriad of pain problems that have failed all other management and discusses the reasons that targeted drug delivery may be an underutilized therapy.
Prof. Dr. David M. Schultz
Dr. Alaa Abd-Elsayed
Guest Editors
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Keywords
- chronic pain
- targeted spinal drug delivery
