Nanotechnology-Based Approaches for Enhancing Oral Administration of Drugs
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".
Deadline for manuscript submissions: 31 March 2024 | Viewed by 6131
Special Issue Editor
Interests: biodegradable polymers; biopharmaceuticals; drug bioavailability; modified release; pharmaceutical nanotechnology
Special Issue Information
Dear Colleagues,
Oral administration is the most convenient route for drugs, as it increases patient compliance and reduces the risk of most parenteral-related complications. However, the poor solubility and stability of drugs along the gastrointestinal tract are major limitations, preventing their therapeutic effect. Nanotechnology approaches for drug delivery applications have shown remarkable progress in the field of drug delivery, so there is no doubt about its potential to increase the stability and bioavailability of drugs administered by oral route.
Nanotechnology-based drug products may impart drug physicochemical or biological properties providing nanoformulations with new abilities such as targeting specific body areas and bypassing others. A significant impact on drug therapeutic dose and side effect risks can increase treatment efficacy. Nanocrystals are among the most nanotechnology-based drug products being approved in the treatment of several diseases. Whether the nanotechnology approach meets drug properties remains a question which is not to be neglected.
This Special Issue focuses on nanotechnology approaches in oral drug administration, their in vitro and in vivo performance analysis, and scale-up potential. Additionally, toxicity issues and regulatory affairs requirements are critically analyzed towards a successful market introduction.
Dr. Antônio J. Ribeiro
Guest Editor
Manuscript Submission Information
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Keywords
- bioavailability
- drug
- modified release
- nanotechnology
- oral delivery
- pharmacokinetics
- regulatory affairs
- stability
- solubility
- safety