Potential of Nano/Microemulsions for Drugs and Phytochemicals Delivery, 2nd Edition
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".
Deadline for manuscript submissions: 20 August 2024 | Viewed by 631
Special Issue Editors
Interests: pharmaceutical technology; nanotechnology; natural products; essential oils
Special Issues, Collections and Topics in MDPI journals
Interests: nanoemulsions; spontaneous emulsification; skin delivery; intranasal delivery; natural products
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Nanoemulsions consist of nanoscale oil/water dispersions stabilized by an appropriate surfactant system in which the drug is incorporated into the oil core and/or adsorbed at the interface. They emerged from the parenteral emulsions more than fifty years ago as they offered an appealing alternative for the administration of poorly water-soluble drugs due to their biocompatibility, stability, ability to reduce the toxicity of cytotoxic drugs, and ability to protect drugs from degradation. Nanoemulsions can be prepared using simple and easy scale-up techniques that enable the solubilization of high quantities of hydrophobic compounds, which represent the majority of new chemical- and plant-based entities. In addition, they are the most deeply studied nanostructure systems to encapsulate essential oils, that replace the oily core conferring to its bioactivities. With specific excipients, such as surfactants and polymers, physicochemical properties are improved providing gains in mucoadhesiveness, permeability, and interaction with biological membranes. In this context, the advantages of these relatively simple colloidal systems have expanded their use from the parenteral to other administration routes, such as oral, transdermal, ocular, and nasal.
Taking into consideration the advantages of nanoemulsions, for this Special Issue, original research and review articles addressing recent advances of nanoemulsions formulations for drugs and phytochemicals delivery using different routes of administration are welcomed.
Prof. Dr. Letícia Scherer Koester
Prof. Dr. Helder Teixeira
Guest Editors
Manuscript Submission Information
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Keywords
- nanoemulsions
- natural products
- essential oils
- drugs
- high-pressure homogenization
- spontaneous emulsification
- microfluidization
- biocompatiblity
- parenteral
- oral
- nasal
- transdermal
- ocular
