Novel Applications of Modern Excipients in Advanced Pharmaceutical Products
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Pharmaceutical Technology, Manufacturing and Devices".
Deadline for manuscript submissions: 31 May 2024 | Viewed by 5598
Special Issue Editors
Interests: pharmaceutical technology; formulation development; direct compression; excipients; OSDF; improvement of drug solubility
Interests: pharmaceutical technology; oral dosage forms; skin penetration and permeation
Special Issue Information
Dear Colleagues,
Practically every pharmaceutical product, whether in solid or liquid form, contains at least one excipient in addition to one or more active ingredients. Excipients are inert components, other than drug substances, which do not exert a pharmacological effect in the doses used. Nevertheless, they are essential in pharmaceutical formulations, ensuring easy and safe drug administration. Although most excipients are considered inert, they are often used for specific purposes. For example, in the field of technology of oral solid dosage forms, they facilitate technological processes such as granulation, tabletting, encapsulation, and give the final drug product the required physical properties, guaranteeing stability and efficacy.
Most scientists and formulation experts concentrate on drug substances, which are the most important components of medicinal preparations. In this Special Issue, we would like to more closely examine various excipients used in pharmaceutical technology, their solubility, rheological and functional characteristics, as well as their impact on the final product. Furthermore, we would like to explore the impact of origin and the method of production on their structure, morphology and physical, chemical, or functional characteristics. An interesting aspect is the constantly evolving quality and safety requirements (e.g., regarding nitrosamine or elemental impurities) as well as market trends (e.g., the demand for vegan, non-GMO, lactose-free products) and how contemporary excipients are responding to them.
Dr. Daniel Zakowiecki
Prof. Dr. Krzysztof Cal
Dr. Tobias Heß
Guest Editors
Manuscript Submission Information
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Keywords
- pharmaceutical excipients
- inactive ingredients
- preformulation/formulation
- drug-excipient compatibility
- particle size, shape and morphology
- oral solid dosage forms
- solubility/dissolution rate
- chemical and physical stability
- manufacturing process
