Editorial Board Members’ Collection Series: Progress and Challenges of Gene Delivery Systems
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Gene and Cell Therapy".
Deadline for manuscript submissions: 31 October 2024 | Viewed by 2537
Special Issue Editors
Interests: targeting drug delivery; nanotechnology and biotechnology
Interests: nucleic acid delivery; nanodiamonds; cationic gemini lipids; self-assembling nanoparticles; small angle X-ray scattering; flow cytometry; radiopharmaceuticals
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In the last few decades, nucleic acid-based therapy has achieved rapid development leading to the approval of some gene therapeutics. However, the instability, short half-life, and membrane impermeability severely hinder the efficient delivery of gene drugs. Development of safe and efficient delivery systems remains the key issue to advance gene therapy. Viral vectors and non-viral vectors, the two main delivery systems at present, have their own advantages and disadvantages. Nanomaterial-based non-viral vectors, including polymers, dendrimers, liposomes, lipid nanoparticles, peptides, and inorganic nanoparticles, have the advantages of safety, non-immunogenicity, and ease of massive production and have been extensively explored for gene therapy. To promote their clinical translation, researchers have tried various strategies to improve delivery efficiency and reduce off-target effects. This issue focuses on the latest progress of nucleic acid delivery systems and highlights the challenges for their translation into clinic, aiming to present a fundamental understanding of this field.
Prof. Dr. Xianrong Qi
Prof. Dr. Ildiko Badea
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
