Special Issue "Advanced Strategies in Drug Design and Development of Small Molecules as Therapeutic Agents"

A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Medicinal Chemistry".

Deadline for manuscript submissions: 20 December 2023 | Viewed by 112

Special Issue Editor

Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Ampl. Polifunzionale, Via P. Bucci, 87036 Arcavacata di Rende, Italy
Interests: drug design; small molecules; natural compounds; protein targeting; anticancer; antiviral; metabolic disorders
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Despite the recent progress in drug research, there are still many concerns that need to be addressed in order to develop new and efficient therapeutics to overcome the side effects caused by conventional drugs.

Accordingly, the research of new active molecules is currently a compelling goal in medicinal chemistry. 

In recent decades, computational methods have become an essential and highly effective tool in drug design and development, allowing for significant advantages in terms of time and cost reduction and thus accelerating the entire drug discovery process.

This Special Issue aims to highlight current efforts towards innovative strategies for the design and development of small molecules, both of natural or synthetic origin, as drug candidates, with the aid of computational methods, such as molecular docking, virtual screening, pharmacophore modeling, QSAR modeling, and chemometric applications in forced degradation studies.

Its content will have to focus on advanced drug discovery approaches, including in silico identification of natural or synthetic therapeutic agents, structure–activity relationship definition, and the design of convenient synthetic strategies for new effective agents.

Reports on the biological and computational evaluation of newly synthesized small molecules as drug candidates or currently in clinical use will be considered as well.

Dr. Fedora Grande
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers

This special issue is now open for submission.
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