Viral and Bacterial Pathogens in Gastrointestinal Cancer
A special issue of Pathogens (ISSN 2076-0817).
Deadline for manuscript submissions: closed (31 March 2022) | Viewed by 7058
Special Issue Editor
Interests: Barrett’s oesophagus; carcinogenesis; Epstein–Barr virus; gastric cancer; Helicobacter pylori; human papillomavirus; microbiome; oesophageal cancer; pathogens
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Bacteria and viruses have long been incriminated in the development of malignancy. In fact, infections are associated with 20% of human cancers. Several viruses are known to be tumorigenic, including human papillomavirus (cervical, head and neck, anal, penile and vulval cancers), Epstein–Barr virus (8-10% of gastric cancer and nasopharyngeal carcinomas), hepatitis B and C (hepatomas) and human T-cell leukaemia virus-1 (T-cell leukaemias). More recently, HPV has been associated with Barrett’s dysplasia and oesophageal adenocarcinoma. The association between HPV and oesophageal squamous cell carcinoma remains contentious, despite numerous studies having been undertaken on the topic. Helicobacter pylori and gastric carcinoma is the archetypal model of a bacterium causing tumours in humans, so much so that it has been classified as a Class I carcinogen by the World Health Organization (1994) and the International Agency on Research on Cancer (2010). Other gut microbiota associated with gastro-intestinal cancer include Streptococcus bovis, Fusobacterium and Salmonella Enteritidis, which have been associated with colon cancer. Similarly, chronic Salmonella Typhi infection has been implicated in carcinoma of the gallbladder.
This Special Issue is aimed at broadening the knowledge base on the role of pathogens in gastro-intestinal cancer in an ever expanding and exciting field. The Guest Editor welcomes both original and review articles which illuminate the complex relationship between humans, pathogens and gastro-intestinal cancers. Topics may include (but are not limited to) epidemiology, pathophysiology, genomic, diagnostic (biomarker) and validation studies as well as investigations that provide prognostic data.
Prof. Shan Rajendra
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- Barrett’s oesophagus
- carcinogenesis
- Epstein–Barr virus
- gastric cancer
- Helicobacter pylori
- human papillomavirus
- microbiome
- oesophageal cancer
- pathogens
