Pathogenesis and Treatment of Giardiasis
A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Parasitic Pathogens".
Deadline for manuscript submissions: 15 May 2024 | Viewed by 2929
Special Issue Editors
Interests: cell biology of Giardia lamblia; pathophysiological mechanisms in giardiasis
Special Issue Information
Dear Colleagues,
Giardia lamblia (syn., G. intestinalis, G. duodenalis) is a protozoan parasite that causes acute diarrhea in humans. Giardiasis, the disease caused by Giardia species, is a widespread infection transmitted among humans and occasionally from animals to humans. Direct contact with contaminated feces or feces-contaminated water and food is the main source of infection. Although distributed worldwide, infection with Giardia tends to occur in confined outbreaks, especially in low- and middle-income countries, with or without poor water supply and sanitation. The disease is characterized by flatulence, abdominal distention and cramps followed by watery diarrhea that later becomes bulky and greasy. Giardiasis is self-limiting in most of infected individuals, but can evolve to chronic or post-infectious gastrointestinal complications. In poor-resource settings, giardiasis is considered a public health problem because it is associated with malnutrition and growth failure in young children.
Substantial progress is being made in understanding the pathogenesis and potential pathophysiological mechanisms behind Giardia-associated diarrhea, and this may lead to novel therapeutic approaches. This Special Issue aims to gather contributions from basic sciences and clinical research to examine the pathophysiology, clinical features, and therapy in giardiasis.
Dr. Renata Rosito Tonelli
Dr. Semíramis Guimarães
Guest Editors
Manuscript Submission Information
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Keywords
- infectious diasease
- intestinal parasite
- diarrhea
- pathophysiological mechanisms
- therapy
