Beyond the Conductivity—The Impact of Neuroplasticity in Health and Disease

A special issue of NeuroSci (ISSN 2673-4087).

Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 3667

Special Issue Editor


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Guest Editor
Department of Molecular Physiology and Neurobiology, University of Wrocław, Sienkiewicza 21, 50-335 Wrocław, Poland
Interests: neuroplasticity; astrocyte-neuron crosstalk; moonlighting proteins; mitochondrial homeostasis; neuronal energetic homeostasis

Special Issue Information

Dear Colleagues,

From the phenomena of learning and remembering, through to meditation and the targeting of molecular mechanisms of psychiatric disorders, neuroplasticity plays a crucial role in multiple brain changes and adaptations by altering its structure and function. Neuroplasticity not only includes morphological changes but also biochemical alternations and modifications of the expression of neurons’ genes. Broadening knowledge about neuroplasticity is a huge opportunity to understand the pathophysiology of neurological and psychiatric disorders. At this very moment, neuroplasticity is key to the treatment of many psychiatric diseases (e.g., depressive episodes and major depressive disorder, obesity, suicidal ideation), unilateral cerebral palsy, rehabilitation after stroke, and more.

In this Special Issue, we would like to discuss brain functions in which neuroplasticity plays an important or even crucial role, and how the understanding of the mechanisms of neuroplasticity can improve diagnostic and treatment strategies of various brain diseases.

We would like to express our sincere gratitude to Mr. Jakub Turlik for his conscientious assistance and support to this Special Issue.

Dr. Przemysław Duda
Guest Editor

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Published Papers (1 paper)

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Research

19 pages, 334 KiB  
Article
Neuroplasticity as a Foundation for Decision-Making in Space
by Margaret Boone Rappaport and Christopher J. Corbally
NeuroSci 2022, 3(3), 457-475; https://doi.org/10.3390/neurosci3030033 - 9 Aug 2022
Cited by 3 | Viewed by 3108
Abstract
This is an exploratory review of two very recent, intersecting segments of space science: neuroplasticity in space, and decision-making in space. The high level of neuroplasticity in humans leads to unfortunate neurological and physical deconditioning while the body adjusts to the new space [...] Read more.
This is an exploratory review of two very recent, intersecting segments of space science: neuroplasticity in space, and decision-making in space. The high level of neuroplasticity in humans leads to unfortunate neurological and physical deconditioning while the body adjusts to the new space environment. However, neuroplasticity may also allow recovery and continued functioning of decision-making at a level necessary for mission completion. Cosmic radiation, microgravity, heightened levels of carbon dioxide in spacecraft, and other factors are being explored as root causes of neurological and physical deconditioning in space. The goal of this paper is to explore some of the lines of causation that show how these factors affect the capacity of humans to make decisions in space. Either alone or in groups, it remains essential that humans retain an ability to make decisions that will save lives, protect equipment, complete missions, and return safely to Earth. A final section addresses healthcare, medical intervention, and remediation that could help to “harness” neuroplasticity before, during, and after spaceflight. The dual nature of human neuroplasticity renders it both a cause of problems and also potentially the foundation of remediation. The future of research on both neuroplasticity and human decision-making promises to be full of surprises, both welcome and otherwise. It is an exciting time in research on space medicine. Full article
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